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Pyoderma Gangrenosum and Superimposed Infection: A Case Report
Elizabeth M Gavioli1, Michael Casias, Linda Ngo
1Elizabeth M. Gavioli, PharmD, is Assistant Professor of Pharmacy Practice, Arnold & Marie Schwartz College of Pharmacy and Health Sciences, 1 University Plaza, Brooklyn, NY, and Clinical Pharmacy Specialist, Mount Sinai Beth Israel, First Avenue at 16th St, New York. Michael Casias, PharmD, is Assistant Professor of Pharmacy Practice, Rutgers, The State University of New Jersey, Piscataway Township, NJ. Linda Ngo, PharmD, is Pharmacist, New York Presbyterian Weill Cornell Medical Center, New York, NY. The authors have disclosed no financial relationships related to this article. Submitted May 17, 2019; accepted in revised form September 13, 2019.
Pyoderma gangrenosum (PG) is a rare inflammatory skin condition. This case highlights the risk of superimposed bacterial infections, specifically Pseudomonas aeruginosa and Bacteroides fragilis, following intralesional corticosteroid treatment for PG.
Area of Science:
- Dermatology
- Infectious Diseases
- Immunology
Background:
- Pyoderma gangrenosum (PG) is a rare, ulcerative inflammatory condition often misdiagnosed as infection.
- Standard treatment involves immunosuppressants, which can increase infection risk.
- Intralesional corticosteroid therapy is sometimes used for localized PG.
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