Related Experiment Video
Updated: Dec 21, 2025

Endobronchial Ultrasound-guided Intratumoral Injection of Cisplatin for the Treatment of Isolated Mediastinal Recurrence of Lung Cancer
Published on: February 12, 2017
Unexpected radiation pneumonitis after SIRT with significant decrease in DLCO with internal radiation exposure: a
Selin Kesim1, Tunc Ones2, Emel Eryuksel3
1Department of Nuclear Medicine, Marmara University Istanbul Pendik Education and Research Hospital, Fevzi Çakmak Mah. Muhsin Yazicioglu Cad. No:10 Ust Kaynarca / Pendik, 34899, Istanbul, Turkey.
Selective Internal Radiation Therapy (SIRT) can cause radiation pneumonitis (RP), a severe lung complication. Pulmonary diffusion capacity (DLCO) can help quantify RP severity and guide timely steroid treatment after SIRT.
Area of Science:
- Oncology
- Nuclear Medicine
- Pulmonology
Background:
- Selective Internal Radiation Therapy (SIRT) using Yttrium-90 microspheres treats malignant hepatic tumors.
- Microsphere shunting to the lungs is a risk, predictable via lung scintigraphy.
- Radiation pneumonitis (RP) is a rare but severe complication of SIRT, requiring prompt steroid treatment.
Related Concept Videos
Radiological Investigation III: Pulmonary Angiogram and PET Scan
Pulmonary Angiogram
A Pulmonary Angiogram is an invasive procedure involving injecting a contrast medium through a catheter threaded into the pulmonary artery or the right side of the heart to visualize the pulmonary vasculature. Computed Tomography (CT) scans have mainly replaced this...
Radiological Investigation II: MRI and Ventilation Perfusion Scan
Magnetic Resonance Imaging (MRI) and Ventilation Perfusion Scans are two radiological investigations that offer detailed diagnostic images of the body, particularly lung structures.
MRI
MRI uses magnetic fields and radiofrequency signals to distinguish between normal and abnormal tissues. This technology provides a more detailed diagnostic image than CT scans, enabling it to characterize pulmonary nodules, stage bronchogenic carcinoma, and evaluate inflammatory activity in...

