Related Experiment Video
Updated: Dec 21, 2025
07:50
Global and Current Research Trends of Single-Cell Sequencing in Cancer: A Bibliometric and Visualization Study
Published on: April 18, 2025
760
Age-specific cancer rates: a bird's-eye view on progress
Silvia Rizzi1, Maarten Wensink1, Linda Juel Ahrenfeldt2
1Unit of Epidemiology, Biostatistics and Biodemography, Department of Public Health, University of Southern Denmark, Odense, Denmark; Interdisciplinary Centre on Population Dynamics, University of Southern Denmark, Odense, Denmark.
Annals of Epidemiology
|May 21, 2020
Summary
Cancer incidence rose 22% over 26 years, but mortality rates fell by 22% across all ages. This indicates significant progress in cancer medicine and treatment effectiveness.
Area of Science:
- Oncology
- Epidemiology
- Public Health
Background:
- Cancer remains a leading cause of morbidity and mortality worldwide.
- Understanding temporal trends in cancer incidence and mortality is crucial for evaluating progress in cancer control.
Purpose of the Study:
- To analyze time trends in age-specific cancer incidence and mortality rates over the past 26 years.
- To assess progress in cancer medicine and treatment efficacy.
Main Methods:
- Utilized population-based cancer registries from Denmark, Finland, Norway, Sweden, and the Netherlands (1990-2016).
- Analyzed age-specific incidence and mortality rates for all cancer sites combined.
Main Results:
- Cancer incidence increased by approximately 22% across all age groups in the studied countries.
- Cancer mortality decreased by approximately 22% across all age groups, with exceptions in older populations in some Nordic countries.
- Observed trends suggest earlier cancer detection and improved treatment outcomes.
Conclusions:
- The study highlights substantial progress in cancer medicine over the last quarter century.
- Declining mortality rates, despite rising incidence, underscore the effectiveness of advancements in cancer diagnosis and therapy.
Related Concept Videos
01:21Cancer Survival Analysis
578
Cancer survival analysis focuses on quantifying and interpreting the time from a key starting point, such as diagnosis or the initiation of treatment, to a specific endpoint, such as remission or death. This analysis provides critical insights into treatment effectiveness and factors that influence patient outcomes, helping to shape clinical decisions and guide prognostic evaluations. A cornerstone of oncology research, survival analysis tackles the challenges of skewed, non-normally...
578
02:07Tumor Progression
7.1K
Tumor progression is a phenomenon where the pre-formed tumor acquires successive mutations to become clinically more aggressive and malignant. In the 1950s, Foulds first described the stepwise progression of cancer cells through successive stages.
Colon cancer is one of the best-documented examples of tumor progression. Early mutation in the APC gene in colon cells causes a small growth on the colon wall called a polyp. With time, this polyp grows into a benign, pre-cancerous tumor. Further...
Colon cancer is one of the best-documented examples of tumor progression. Early mutation in the APC gene in colon cells causes a small growth on the colon wall called a polyp. With time, this polyp grows into a benign, pre-cancerous tumor. Further...
7.1K
02:59Cancer Prevention
7.5K
Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
Some...
Some...
7.5K
01:30Cancer Vaccines
868
Cancer treatment vaccines are a rapidly evolving field that offers a promising approach to immunotherapy. Unlike traditional vaccines that prevent diseases, cancer treatment vaccines are designed to treat existing cancers by stimulating the immune system to recognize and attack cancer cells.
Cancer vaccines come in two categories: preventive (prophylactic) and treatment (active). Preventive vaccines, such as the Human Papillomavirus (HPV) vaccine, protect against viruses that cause certain...
Cancer vaccines come in two categories: preventive (prophylactic) and treatment (active). Preventive vaccines, such as the Human Papillomavirus (HPV) vaccine, protect against viruses that cause certain...
868
02:18Cancer
53.2K
Cancers arise due to mutations in genes involved in the regulation of cell division, which leads to unrestricted cell proliferation. Modern science and medicine have made great strides in the understanding and treatment of cancer, including eradicating cancer in some patients. However, there is still no cure for cancer. This is largely due to the fact that cancer is a large group of many diseases.
53.2K
02:57Targeted Cancer Therapies
8.5K
The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against...
There are several types of targeted therapies against...
8.5K