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Updated: Dec 21, 2025

Guidelines and Experience Using Imaging Biomarker Explorer IBEX for Radiomics
Published on: January 8, 2018
Emerging methods in radiology
B Theek1,2, T Nolte1, D Pantke1
1Institute for Experimental Molecular Imaging, Medical Faculty, RWTH Aachen International University, Forckenbeckstraße 55, 52074, Aachen, Germany.
Advancements in medical imaging, including computed tomography (CT), magnetic resonance imaging (MRI), and positron emission tomography (PET), offer enhanced diagnostic capabilities. Future innovations promise improved sensitivity, quantitative analysis, and integrated diagnostics for personalized medicine.
Area of Science:
- Radiology and Medical Imaging
- Biomedical Engineering
- Diagnostic Technologies
Background:
- Recent decades have seen rapid advancements in imaging modalities, significantly influencing diagnostic capabilities.
- Improved resolution, faster acquisition, and functional/molecular imaging provide groundbreaking insights into tissue pathophysiology.
- Current research focuses on enhancing device/contrast media applications, sensitivity, and quantitative value.
Purpose of the Study:
- To provide an overview of technological innovations poised to enhance future clinical imaging.
- To highlight emerging diagnostic options stemming from these technological advancements.
- To discuss the clinical introduction of radiomic image evaluation, including its opportunities and challenges.
Main Methods:
- Review of established imaging methods (CT, MRI, ultrasound, PET, SPECT).
- Exploration of novel imaging techniques like magnetic particle imaging (MPI), optical imaging, and photoacoustics.
- Discussion of advanced data processing, multiparametric analysis, and integrated diagnostics.
Main Results:
- Technological innovations are expanding the application scope of imaging devices and contrast agents.
- New methods improve sensitivity, quantitative accuracy, and multiparametric data analysis.
- Radiomics offers new avenues for image evaluation, though clinical integration requires further development.
Conclusions:
- Future imaging technologies will enable a more detailed understanding of pathophysiological relationships at both whole-body and tissue levels.
- Enhanced imaging will facilitate better drug efficacy assessment, patient preselection for therapies, and improved treatment monitoring.
- The integration of interdisciplinary diagnostics will significantly transform and enrich the field of radiology.
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