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Updated: Dec 21, 2025

Microfluidic Flow Chambers Using Reconstituted Blood to Model Hemostasis and Platelet Transfusion In Vitro
Published on: March 19, 2016
[Blood, where no blood should be]
Daniel M Handzel1, Aisha Alani, Roman P Handzel
1Augenärzte im Altstadt-Carree, Augenzentrum Osthessen, Dalbergstr. 22, 36037, Fulda, Deutschland. dhandzel@augenaerzte-fulda.de.
Intraocular ischemia can cause excessive vascular endothelial growth factor (VEGF) production, leading to abnormal blood vessel growth in the eye. This case study details lens neovascularization resulting from central retinal vein occlusion.
Area of Science:
- Ophthalmology
- Vascular Biology
- Retinal Diseases
Background:
- Intraocular ischemia is a known trigger for vascular endothelial growth factor (VEGF) overexpression.
- VEGF-induced neovascularization can affect various eye segments, including the iris and retina.
- Neovascularization represents abnormal blood vessel formation, often associated with poor prognosis.
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