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Paper chromatographic characterization of an extracellular biologically active compound from Coelastrum sphaericum
1Department of Biological Sciences, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Argentina.
Abstract:
A non-cytotoxic, wide antiviral spectra compound was isolated from the lyophilized media of axenic cultures of the green alga Coelastrum sphaericum var. dilatatum. After acid hydrolysis, polyenic-like fractions were liberated from the same compound with inhibitory effect against Candida albicans. Biochromatographic and spectrophotometric results demonstrated that the product included a glycosidic fraction associated with a nucleotidic component.