Related Experiment Videos
Staphylococcus haemolyticus: cocarde growth around imipenem disks
1Institut für Medizinische Mikrobiologie und Hygiene, Universität des Saarlandes, BRD.
Chemotherapy
|January 1, 1988
Summary
Twelve drug-resistant Staphylococcus haemolyticus strains showed a unique double zone of inhibition around imipenem disks. This unusual finding was specific to this species during the study period.
Area of Science:
- Microbiology
- Clinical Infectious Diseases
- Antimicrobial Resistance
Background:
- Coagulase-negative staphylococci (CoNS) are significant opportunistic pathogens.
- Multiple-drug resistance (MDR) in staphylococci poses a therapeutic challenge.
- Unusual phenotypic traits can indicate specific species or resistance mechanisms.
Purpose of the Study:
- To identify staphylococcal species exhibiting cocarde growths (double zones of inhibition) around imipenem disks.
- To characterize this unique phenotypic trait in clinical isolates.
Main Methods:
- Isolation and identification of coagulase-negative staphylococci from diverse clinical sources.
- Antimicrobial susceptibility testing using 10 microgram imipenem disks.
- Phenotypic characterization of inhibition zones, specifically noting cocarde growths.
Main Results:
- Twelve MDR isolates displayed cocarde growths around imipenem disks.
- All twelve isolates were identified as Staphylococcus haemolyticus.
- Staphylococcus haemolyticus was the sole CoNS species exhibiting this trait during the 7-month observation period.
Conclusions:
- Staphylococcus haemolyticus possesses a unique phenotypic characteristic of double zones of inhibition around imipenem.
- This trait may serve as a potential marker for identifying Staphylococcus haemolyticus among CoNS.
- Further investigation into the mechanisms underlying this phenomenon is warranted.