Tunable Fe₃O₄ Nanorods for Enhanced Magnetic Hyperthermia Performance

Magnetic hyperthermia is one of the most promising techniques for treating gynecological cancer, where magnetite (Fe₃O₄) is the most common nanomaterial used as a magnetic hyperthermia agent. Here, we demonstrate that optimal Fe₃O₄ nanorods (NRs) can act as a magnetic hyperthermia agent with higher specific absorption rate (SAR), which is mostly attributed to their enhanced surface anisotropy. As a result, Fe₃O₄ NRs could effectively hinder the growth of gynecological cancer cells in nude mice models, again demonstrating its good magnetic heating properties. These results provide a powerful basis for the development of an ideal magnetic hyperthermia agent with enhanced SAR, thereby effectively treating gynecological cancer in clinical practice.