Attractiveness and neural processing of infant faces: effects of a facial abnormality but not dopamine

Adults' caregiving responses toward infants may have important origins in the perception and processing of infant cues as well as the motivation to attend to these cues. Moreover, some biological processes, such as dopaminergic neurotransmission, may be crucially involved. Although infant stimuli are generally experienced as cute and rewarding, infants with a visible disability may be regarded much less favorably than others, perhaps dependent on differences in perception, motivation, and neural processing. The current study investigated effects of administered dopamine on the perceived attractiveness and neurophysiological indices of attention and processing (i.e., the P1, P2, and N170 components of the event-related potential) of infant faces with and without a cleft lip. No evidence for effects of dopamine was found, but we replicated the finding that the decreased attractiveness of infants with a cleft lip was mediated by decreased configural face processing (smaller N170 amplitudes), but not more general attentional and/or executive processing (P2). The current findings show once again the unfavorable consequences of a cleft lip, but also highlight the importance of combining and relating measures across various levels of analysis and underscore the importance of replication.