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Dinitrosyliron Complex [(PMDTA)Fe(NO)2]: Intermediate for Nitric Oxide Monooxygenation Activity in Nonheme Iron

Shan Lu1, Tzung-Wen Chiou1,2, Wei-Liang Li1

  • 1Department of Chemistry, National Tsing Hua University, Hsinchu 30013, Taiwan.

Inorganic Chemistry
|May 22, 2020
PubMed

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Nitrous acid is a relatively weak and unstable acid prepared in situ by the reaction of sodium nitrite and cold, dilute hydrochloric acid. In an acidic solution, the nitrous acid undergoes protonation when it loses water to form a nitrosonium ion—an electrophile. Nitrous acid reacts with primary amines to give diazonium salts. The reaction is called diazotization of primary amines.
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