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Updated: Dec 20, 2025

Protocol and Guidelines for Point-of-Care Lung Ultrasound in Diagnosing Neonatal Pulmonary Diseases Based on International Expert Consensus
Published on: March 6, 2019
Neonatal Aerodigestive Disorders: Epidemiology and Economic Burden
1Center for Perinatal Research, Abigail Wexner Research Institute at Nationwide Children's Hospital, Columbus, OH, USA; Division of Neonatology, Department of Pediatrics, College of Medicine, The Ohio State University, Columbus, OH, USA; Division of Epidemiology, College of Public Health, The Ohio State University, Columbus, OH, USA.
Insights
Aerodigestive disorders impact breathing and eating in infants, affecting development and lifelong health. Early identification and management are crucial for preventing long-term issues and reducing healthcare costs.
Area of Science:
- Pediatric Medicine
- Gastroenterology
- Pulmonology
Background:
- Aerodigestive disorders involve the airway and upper gastrointestinal tract, intricately linked from fetal development.
- Effective respiration and feeding in infants depend on coordinated swallowing and aspiration prevention.
- These conditions can lead to significant lifelong morbidities and substantial healthcare expenditures.
Purpose of the Study:
- To outline the epidemiology and prevalence of common aerodigestive disorders.
- To highlight the significance of oral feeding at discharge as a neurodevelopmental marker.
- To provide an overview of associated medical costs.
Main Methods:
- Literature review of aerodigestive disorder epidemiology.
- Analysis of prevalence data for common conditions.
- Compilation of available research on medical costs.
Main Results:
- Prevalence data for key aerodigestive disorders presented.
- Oral feeding at discharge identified as a critical developmental milestone.
- Information on associated healthcare costs discussed.
Conclusions:
- Aerodigestive disorders represent a significant health concern with long-term implications.
- Understanding epidemiology and costs is vital for resource allocation and patient care.
- Focus on neurodevelopmental outcomes like oral feeding is essential.
Abstract:
Aerodigestive disorders, those affecting the upper and lower airway or upper gastrointestinal tract, are interrelated anatomically during fetal development and functionally after birth. Successful respiration and feeding requires careful coordination to promote effective swallowing and prevent aspiration. I describe the epidemiology, including the prevalence of the most common aerodigestive disorders. The ability of an infant to feed by mouth at discharge, without a surgically placed feeding tube, is an important neurodevelopmental marker. Therefore, aerodigestive disorders have a high potential for lifelong morbidities and health care expenditures. When available, published research on related medical costs for these disorders is provided.
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