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Functional Polymers Structures for (Bio)Sensing Application-A Review.
Kamila Spychalska1, Dorota Zając1, Sylwia Baluta1
1Faculty of Chemistry, Wrocław University of Science and Technology, 50-137 Wrocław, Poland.
Polymers
|May 24, 2020
Summary
Polymeric materials are crucial for developing advanced biosensors and lab-on-a-chip (LOC) devices. These versatile polymers offer biocompatibility and cost-effectiveness, enhancing analytical tool sensitivity and selectivity for medical diagnostics.
Area of Science:
- Materials Science
- Biotechnology
- Analytical Chemistry
Background:
- Biosensors and lab-on-a-chip (LOC) devices require advanced materials for fabrication and functionality.
- Polymeric materials offer unique properties suitable for developing next-generation analytical tools.
Purpose of the Study:
- To review polymeric materials for biosensor and LOC device development.
- To highlight the role of specific polymers in enhancing sensor performance and enabling portable diagnostics.
Main Methods:
- Review of conductive polymers (conjugated microporous polymers, polymer gels), composites, and molecularly imprinted polymers.
- Analysis of their influence on the design and fabrication of bio(sensors) and LOC devices.
Main Results:
- Polymeric materials are promising for LOC device manufacturing and as immobilization surfaces for biomolecules.
- The use of these polymers can significantly improve the sensitivity and selectivity of analytical tools.
- Key polymer types discussed include conductive polymers, composites, and molecularly imprinted polymers.
Conclusions:
- Polymeric materials are essential for creating advanced, portable diagnostic tools like LOC devices.
- These materials provide a biocompatible, cost-effective, and flexible platform for biosensor development.
- The integration of specific compounds onto these polymer surfaces enhances analytical capabilities, particularly for medical diagnostics.
Keywords:
compositesconducting polymerselectrochemical sensinglab-on-a-chipmicrofluidicsmolecularly imprinted polymers
