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Nano Phytomedicine Based Delivery System for CNS Disease
Mohammed Asadullah Jahangir1, Chettupalli Anand2, Abdul Muheem3
1Department of Pharmaceutics, Nibha Institute of Pharmaceutical Sciences, Rajgir, Nalanda-803116, Bihar, India.
Current Drug Metabolism
|May 24, 2020
Summary
Herbal medicines offer safer, cost-effective treatments, with nanotechnology enhancing their effectiveness. Nano-phytomedicines show promise for treating Central Nervous System (CNS) disorders by improving drug delivery and bioavailability.
Area of Science:
- Pharmacology and Traditional Medicine
- Nanotechnology in Drug Delivery
Background:
- Herbal medicines, used for centuries, are increasingly recognized by scientists for their therapeutic potential and fewer side effects.
- The global herbal medicine market is valued at approximately US $62 billion, driven by efficacy, low cost, and accessibility.
- Safety and efficacy are crucial for the commercialization of herbal medicines.
Purpose of the Study:
- To review herbal medicines with significant activity in Central Nervous System (CNS) disorders.
- To explore the application of nano-phytomedicine delivery systems for enhancing herbal drug efficacy.
Main Methods:
- Review of scientific literature on herbal medicines and their CNS activities.
- Analysis of nanotechnology-based approaches for improving herbal medicine formulation.
- Discussion of novel delivery systems like niosomes, liposomes, nanospheres, and phytosomes.
Main Results:
- Nanotechnology significantly enhances the bioactivity and bioavailability of herbal medicines.
- Methods such as size reduction, polymer conjugation, and surface modification improve solubility and permeability.
- Nano-phytomedicines offer improved therapeutic outcomes for CNS disorders.
Conclusions:
- Nano-phytomedicines represent a promising advancement in the delivery of herbal drugs, particularly for CNS disorders.
- Nanotechnology-based formulations can overcome limitations of traditional herbal medicine delivery, increasing efficacy and patient compliance.
- Further research into nano-phytomedicines can unlock the full therapeutic potential of traditional herbal remedies.
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