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Updated: Dec 20, 2025

Quantification of the Potential Impact of Glyphosate-Based Products on Microbiomes
Published on: January 10, 2022
Glyphosate and its toxicology: A scientometric review
Nédia de Castilhos Ghisi1, Natana Raquel Zuanazzi2, Thomaz Mansini Carrenho Fabrin3
1Graduate Program in Biotechnology (PPGBIOTEC), Federal University of Technology-Paraná, Campus Dois Vizinhos (UTFPR-DV), Brazil.
This study analyzed global research on glyphosate, finding that publication volume correlates with a country's GDP. The USA leads in glyphosate research, with toxicology studies focusing on habitat alteration and presence in drinking water.
Area of Science:
- Environmental Science
- Toxicology
- Ecology
Background:
- Glyphosate is a widely studied herbicide with extensive global research.
- No systematic scientometric review of glyphosate research existed prior to this study.
- Understanding publication patterns is crucial for assessing research focus and investment.
Purpose of the Study:
- To conduct a scientometric analysis of publication patterns in glyphosate research.
- To identify leading countries and influential research areas concerning glyphosate.
- To highlight key research themes and knowledge gaps in glyphosate toxicology.
Main Methods:
- Data sourced from Web of Science, focusing on "Glyphosate" topic (10,069 publications).
- A subset of 2077 publications was selected, focusing on "Environmental Sciences", "Toxicology", and "Ecology".
- Analysis performed using CiteSpace, correlating publication data with Gross Domestic Product (GDP) and researcher numbers.
Main Results:
- Publication output strongly correlates with national GDP.
- The USA is the leading country in overall glyphosate publications, followed by Brazil, Canada, and China.
- Key research areas include glyphosate-induced habitat alteration, AMPA, genotoxicity, herbicide mixtures, and presence in drinking water.
Conclusions:
- Research on glyphosate and its toxicology is significantly influenced by economic factors (GDP) and research investment.
- There is a notable concern regarding glyphosate's impact on ecosystems and the need for more research on its genotoxicity and carcinogenicity.
- Further meta-analytical reviews are recommended to consolidate findings and inform sustainable agricultural practices and human health protection.
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