Related Experiment Video
Updated: Dec 20, 2025

Assessment and Evaluation of the High Risk Neonate: The NICU Network Neurobehavioral Scale
Published on: August 25, 2014
Long-term Healthcare Utilization by Medicaid Enrolled Children with Neonatal Abstinence Syndrome
Walter M Taylor1, Yewei Lu2, Shuang Wang3
1Department of Anesthesiology, Columbia University College of Physicians and Surgeons, New York, NY; University of Colorado School of Medicine, Aurora, CO.
Insights
Neonatal abstinence syndrome (NAS) in children does not independently predict higher healthcare use. After accounting for clinical factors, NAS did not lead to more inpatient or emergency visits, but fewer outpatient visits.
Area of Science:
- Pediatrics
- Neonatal Health
- Healthcare Services Research
Background:
- Neonatal abstinence syndrome (NAS) is a growing concern, impacting healthcare resource allocation.
- Understanding long-term healthcare utilization for infants with NAS is crucial for effective resource planning and intervention strategies.
Purpose of the Study:
- To evaluate healthcare utilization in Medicaid-enrolled children diagnosed with neonatal abstinence syndrome (NAS) within the first two years of life.
- To determine if NAS is an independent predictor of increased healthcare utilization after controlling for confounding factors.
Main Methods:
- A retrospective, longitudinal cohort study design was employed, analyzing Medicaid data from New York and Texas.
- Tapered propensity score matching was used to compare children with NAS to similar children without NAS, controlling for demographics and clinical covariates.
- Poisson and negative binomial regression models calculated healthcare utilization ratios (HUR) for inpatient days, emergency department visits, and outpatient visits.
Main Results:
- Initially, children with NAS showed higher inpatient days and emergency department visits.
- After matching on clinical covariates and adjusting for multiple comparisons, these differences were no longer statistically significant for inpatient days and emergency visits.
- Children with NAS had significantly fewer outpatient office visits (HUR, 0.91; P < .0001).
Conclusions:
- Neonatal abstinence syndrome is not an independent predictor of increased healthcare utilization in the first two years of life.
- Observed healthcare utilization differences may be attributed to associated perinatal complications and congenital anomalies rather than NAS itself.
- Findings suggest a need to investigate underlying factors contributing to healthcare use in infants with prenatal drug exposure.
Objective:
To evaluate healthcare utilization in Medicaid enrolled children with neonatal abstinence syndrome (NAS) in the first 2 years of life.
Study Design:
A retrospective, longitudinal cohort study evaluating Medicaid enrolled children born in New York (1999-2011) and Texas (1999-2010) was performed. Healthcare utilization, including inpatient days, emergency department and outpatient visits, and filled prescriptions in children after birth hospitalization was assessed. A tapered propensity-matching methodology was used, matching each child with NAS with 5 children without NAS, first on demographics, then on both demographics and clinical covariates (clinical diagnoses and congenital anomalies at birth). Poisson and negative binomial regression were used to calculate healthcare utilization ratios (HUR).
Results:
In the first 2 years of life, children with NAS (n = 3799) had increased healthcare utilization with more inpatient days and emergency department visits than demographically similar children without NAS. This increased utilization however did not persist after matching on clinical covariates and performing multiple comparisons adjustment (inpatient days [HUR, 1.01; 95% CI, 0.88-1.16; P = .89], total emergency department visits [HUR, 1.06; 95% CI, 1.01-1.11; P = .02]). Children with NAS conversely had 9% fewer outpatient office visits (HUR, 0.91; 95% CI, 0.87-0.95; P < .0001).
Conclusions:
A diagnosis of NAS does not appear to be an independent predictor of increased healthcare utilization in the first 2 years of life. These results differ from some other published studies, but may suggest that the increased healthcare utilization observed in children with NAS is due to higher incidences of perinatal complications and congenital anomalies in children with prenatal drug exposures.
More Related Videos
05:13Preclinical Model of Prenatal Delta-9-Tetrahydrocannabinol Exposure to Assess Its Impact on Neurodevelopmental Outcomes
Published on: February 28, 2025
19:57The Use of Trace Eyeblink Classical Conditioning to Assess Hippocampal Dysfunction in a Rat Model of Fetal Alcohol Spectrum Disorders
Published on: August 5, 2017
Related Concept Videos
Pharmacokinetics in Pediatric Patients: Drug Excretion
Specialized Care Centers and Settings-II
Rural health centers are specialized care facilities in remote locations with very few medical personnel. The primary care providers who run the centers are mostly Registered Nurse Practitioners. Here, emergency treatment is provided to critically ill or injured patients before they are transferred to the closest hospital. Fortunately, due to advancement in technology, many rural healthcare facilities and professionals have easy access to diagnostic and treatment...
Restorative Care
Documentation in Long-Term and Home Healthcare Setting
Long-Term Care Facilities
Substance Use Disorders Affecting Sleep
Understanding the concepts of physical dependence,...
Drug Dosing: Infants and Children