Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Ethics in Research01:56

Ethics in Research

25.3K
Today, scientists agree that good research is ethical in nature and is guided by a basic respect for human dignity and safety. However, this has not always been the case. Modern researchers must demonstrate that the research they perform is ethically sound.
25.3K
Surveys02:16

Surveys

16.5K
Often, psychologists develop surveys as a means of gathering data. Surveys are lists of questions to be answered by research participants, and can be delivered as paper-and-pencil questionnaires, administered electronically, or conducted verbally. Generally, the survey itself can be completed in a short time, and the ease of administering a survey makes it easy to collect data from a large number of people.
16.5K
Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches01:23

Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches

323
Biopharmaceutical studies constitute a vital field aiming to enhance drug delivery methods and refine therapeutic approaches, drawing upon diverse interdisciplinary knowledge. In research methodologies, the choice between controlled and non-controlled studies significantly influences the study's reliability and accuracy.
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast,...
323
Bioavailability Study Design: Healthy Subjects Versus Patients01:15

Bioavailability Study Design: Healthy Subjects Versus Patients

83
Bioavailability studies are essential for evaluating a drug's therapeutic efficacy and understanding its absorption patterns under various physiological conditions. Conducting such studies on target patient populations provides more relevant data by simulating real-world disease states. However, practical challenges often necessitate the use of young, healthy adult volunteers as study subjects.Patients may exhibit altered drug absorption patterns due to the effects of the disease itself,...
83
Blind Procedures02:07

Blind Procedures

12.7K
Ideally, the people who observe and record the children’s behavior are unaware of who was assigned to the experimental or control group, in order to control for experimenter bias. Experimenter bias refers to the possibility that a researcher’s expectations might skew the results of the study. Remember, conducting an experiment requires a lot of planning, and the people involved in the research project have a vested interest in supporting their hypotheses. If the observers knew which...
12.7K
Longitudinal Research02:20

Longitudinal Research

13.0K
Sometimes we want to see how people change over time, as in studies of human development and lifespan. When we test the same group of individuals repeatedly over an extended period of time, we are conducting longitudinal research. Longitudinal research is a research design in which data-gathering is administered repeatedly over an extended period of time. For example, we may survey a group of individuals about their dietary habits at age 20, retest them a decade later at age 30, and then again...
13.0K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

What is the future role of quantum computation in drug discovery?

Emerging topics in life sciences·2026
Same author

Chronic Hypertension in the ED: Physician Response When Hypertension Is or Is not a Reason for the ED Visit.

Academic emergency medicine : official journal of the Society for Academic Emergency Medicine·2026
Same author

Barriers to Optimization of Medical Therapy and the Role of Checklist-Based Decision Support in Heart Failure.

Journal of the American Heart Association·2026
Same author

An Open-Source, Open Data Approach to Activity Classification from Triaxial Accelerometry in an Ambulatory Setting.

ArXiv·2026
Same author

Nonmydriatic Ocular Fundus Imaging in Consecutive Patients With Headache in an Emergency Department.

Neurology. Clinical practice·2026
Same author

Exploration of Antiplasmodium Chemical Space Identifies New Inhibitors of β-Hematin Formation from Areas of Enrichment.

ChemMedChem·2026

Related Experiment Video

Updated: Dec 20, 2025

Working with Human Tissues for Translational Cancer Research
07:48

Working with Human Tissues for Translational Cancer Research

Published on: November 26, 2015

10.3K

Patient and Surrogate Postenrollment Perspectives on Research Using the Exception From Informed Consent: An

Victoria M Scicluna1, Michelle Biros2, Deneil K Harney1

  • 1University of Michigan Medical School, Ann Arbor, MI.

Annals of Emergency Medicine
|May 25, 2020
PubMed
Summary
This summary is machine-generated.

Patient and surrogate attitudes toward exception from informed consent research enrollment were generally positive. However, acceptance of exception from informed consent was lower, particularly among Black participants, highlighting the need for targeted community consultation.

More Related Videos

A Novel Method for Involving Women of Color at High Risk for Preterm Birth in Research Priority Setting
14:43

A Novel Method for Involving Women of Color at High Risk for Preterm Birth in Research Priority Setting

Published on: January 12, 2018

12.4K
Online Explorative Study on the Learning Uses of Virtual Reality Among Early Adopters
07:29

Online Explorative Study on the Learning Uses of Virtual Reality Among Early Adopters

Published on: November 22, 2019

8.5K

Related Experiment Videos

Last Updated: Dec 20, 2025

Working with Human Tissues for Translational Cancer Research
07:48

Working with Human Tissues for Translational Cancer Research

Published on: November 26, 2015

10.3K
A Novel Method for Involving Women of Color at High Risk for Preterm Birth in Research Priority Setting
14:43

A Novel Method for Involving Women of Color at High Risk for Preterm Birth in Research Priority Setting

Published on: January 12, 2018

12.4K
Online Explorative Study on the Learning Uses of Virtual Reality Among Early Adopters
07:29

Online Explorative Study on the Learning Uses of Virtual Reality Among Early Adopters

Published on: November 22, 2019

8.5K

Area of Science:

  • Clinical Trials
  • Informed Consent
  • Patient Experience

Background:

  • Understanding patient and surrogate views on exception from informed consent (EFIC) is crucial for ethical research.
  • Previous studies on EFIC attitudes were limited by small sample sizes, exclusion of pediatric populations, and delayed interviews.

Purpose of the Study:

  • To explore attitudes toward EFIC enrollment in a larger, more contemporary sample.
  • To assess patient and surrogate views on enrollment in the Established Status Epilepticus Treatment Trial (ESETT).

Main Methods:

  • A 10-item survey was administered to participants in the ESEETT, a randomized trial for status epilepticus.
  • The survey assessed attitudes toward trial enrollment, EFIC, and community consultation.
  • Statistical analyses included descriptive statistics, chi-squared, and Fisher's exact tests.

Main Results:

  • 90% of participants agreed or were neutral about their inclusion in the ESEETT.
  • 27% disagreed with enrollment without prospective consent, with Black participants showing higher disagreement rates (36%).
  • Participants identified patients (81%), families (65%), and at-risk individuals (51%) as key groups for community consultation.

Conclusions:

  • General acceptance of trial enrollment was high, but specific acceptance of EFIC was lower.
  • Black participants expressed lower acceptance of EFIC, underscoring racial disparities in attitudes.
  • Findings support targeted community consultation and emphasize the need for improved post-enrollment communication regarding EFIC.