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Related Experiment Video

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TissUUmaps: interactive visualization of large-scale spatial gene expression and tissue morphology data.

Leslie Solorzano1, Gabriele Partel1, Carolina Wählby1

  • 1Department of Information Technology and SciLifeLab, Uppsala University, Uppsala 752 37, Sweden.

Bioinformatics (Oxford, England)
|May 26, 2020
PubMed
Summary
This summary is machine-generated.

TissUUmaps allows rapid visualization of millions of data points on tissue samples. This tool facilitates interactive exploration and data sharing for molecular marker analysis.

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Area of Science:

  • Digital pathology
  • Bioinformatics
  • Computational biology

Background:

  • Visual assessment of scanned tissue samples and molecular markers requires multi-resolution interactive inspection.
  • Efficient handling of image pyramids and data distribution across detail levels is crucial.

Purpose of the Study:

  • To present TissUUmaps, a tool for fast visualization and exploration of large-scale data on tissue samples.
  • To enable interactive inspection of scanned tissue samples and associated molecular markers.

Main Methods:

  • Development of TissUUmaps software for handling large image datasets and molecular data.
  • Implementation of image pyramid management and efficient data distribution strategies.

Main Results:

  • TissUUmaps enables fast visualization and exploration of millions of data points overlaid on tissue samples.
  • The tool supports both web-based and local usage, allowing extraction and sharing of regions of interest and local statistics.

Conclusions:

  • TissUUmaps provides an efficient solution for interactive analysis of high-resolution scanned tissue samples.
  • The software facilitates collaborative research through data sharing and region-of-interest analysis.