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Updated: Aug 18, 2026

Characterization of Membrane Transporters by Heterologous Expression in E. coli and Production of Membrane Vesicles
Published on: December 31, 2019
[Comparative study of bacterial agmatinase inhibition by derivatives of putrescine and aliphatic monoamines]
Abstract:
Aliphatic monoamines and some putrescine derivatives (10(-3) M) are found to inhibit agmatinase from Proteus vulgaris. Constants and the type of inhibition are determined. Investigation of the temperature effect on the inhibition has revealed an exotermic character of this process. Some thermodinamic parameters of agmatinase-anylamine binding reaction are calculated. 1-Guanidobutane is obtained by means of 1-amidobutane guanidilation, and it is found to be more efficient inhibitor than monoamines.
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