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The Israeli Phage Bank (IPB)
Ortal Yerushalmy1, Leron Khalifa1, Naama Gold1
1Institute of Dental Sciences, School of Dentistry, Hebrew University of Jerusalem, Jerusalem 91120, Israel.
Antibiotics (Basel, Switzerland)
|May 28, 2020
Summary
The Israeli Phage Bank (IPB) stores over 300 well-characterized phages for clinical use and research. This phage collection supports phage therapy and personalized medicine by matching phages to bacterial pathogens.
Area of Science:
- Microbiology
- Bacteriology
- Virology
Background:
- Phage therapy relies on extensive phage collections (banks) for clinical applications.
- Phage banks are crucial for matching phages and antibiotics to specific bacterial targets in clinical phage microbiology.
- Establishing a global network of phage banks can advance phage-based solutions for bacterial infections.
Purpose of the Study:
- To describe the Israeli Phage Bank (IPB) at the Hebrew University, Jerusalem.
- To highlight the IPB's current phage collection and its ongoing development.
- To emphasize the role of phage banks in advancing phage therapy.
Main Methods:
- Establishment and maintenance of a phage bank.
- Isolation and characterization of bacteriophages.
- Database management for phage and bacterial strain information.
Main Results:
- The Israeli Phage Bank (IPB) houses over 300 phages.
- The IPB collection targets 16 different bacteria, primarily pathogens.
- Information on the IPB's phage and bacterial holdings is accessible online.
Conclusions:
- The Israeli Phage Bank (IPB) is a significant resource for phage therapy research and clinical applications.
- Continuous phage isolation and characterization are vital for expanding the IPB's utility.
- Online accessibility of phage bank data facilitates research and clinical matching.