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Updated: Dec 20, 2025

Injectable Supramolecular Polymer-Nanoparticle Hydrogels for Cell and Drug Delivery Applications

Injectable Supramolecular Polymer-Nanoparticle Hydrogels for Cell and Drug Delivery Applications

Published on: February 7, 2021

Nanoparticle-hydrogel superstructures for biomedical applications.

Yao Jiang¹, Nishta Krishnan¹, Jiyoung Heo¹

¹Department of NanoEngineering, Chemical Engineering Program, Moores Cancer Center, University of California San Diego, La Jolla, CA 92093, USA.

Journal of Controlled Release : Official Journal of the Controlled Release Society

|May 29, 2020

Summary

This summary is machine-generated.

Nanoparticle-hydrogel superstructures combine the benefits of both components for advanced biomedical applications. These tunable, multifunctional platforms show great promise in drug delivery, tissue engineering, and immune modulation.

Keywords:

Detoxification Drug delivery Hydrogel hybrid Immune modulation Nanomedicine Nanoparticle Tissue engineering

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Last Updated: Dec 20, 2025

Injectable Supramolecular Polymer-Nanoparticle Hydrogels for Cell and Drug Delivery Applications

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Published on: February 7, 2021

Fragmenting Bulk Hydrogels and Processing into Granular Hydrogels for Biomedical Applications

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Published on: May 17, 2022

Gelatin Methacryloyl Granular Hydrogel Scaffolds: High-throughput Microgel Fabrication, Lyophilization, Chemical Assembly, and 3D Bioprinting

Gelatin Methacryloyl Granular Hydrogel Scaffolds: High-throughput Microgel Fabrication, Lyophilization, Chemical Assembly, and 3D Bioprinting

Published on: December 9, 2022

Area of Science:

Biomaterials Science
Nanotechnology
Biomedical Engineering

Background:

Nanoparticle-hydrogel superstructures are gaining traction in biomedical research.
These structures offer tunable and multifunctional platforms by combining nanoparticle and hydrogel properties.
Synergistic combination of components overcomes limitations of using nanoparticles or hydrogels separately.

Purpose of the Study:

To review the synthesis and fabrication methods of nanoparticle-hydrogel superstructures.
To provide an overview of the diverse applications of these advanced materials.
To highlight the clinical potential and future directions of nanoparticle-hydrogel research.

Main Methods:

Review of synthesis and fabrication techniques for nanoparticle-hydrogel composites.
Analysis of existing literature on applications in drug delivery, detoxification, immune modulation, and tissue engineering.

Main Results:

Nanoparticle-hydrogel superstructures can be synthesized and fabricated through various methods.
These superstructures demonstrate efficacy in diverse biomedical applications.
The tunable and multifunctional nature of these platforms is key to their success.

Conclusions:

Nanoparticle-hydrogel superstructures offer significant advantages over individual components.
These platforms exhibit substantial clinical potential for addressing unmet medical needs.
Future research is expected to yield innovative solutions in medicine through further development.