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Updated: Dec 20, 2025

Direct Agroinoculation of Maize Seedlings by Injection with Recombinant Foxtail Mosaic Virus and Sugarcane Mosaic Virus Infectious Clones
Published on: February 27, 2021
Recent advances on the plant manipulation by geminiviruses
Emmanuel Aguilar1, Borja Garnelo Gomez1, Rosa Lozano-Duran1
1Shanghai Center for Plant Stress Biology, CAS Center for Excellence in Molecular Plant Sciences, Chinese Academy of Sciences, Shanghai 201602, China.
Geminiviruses, plant-infecting viruses, hijack host cell machinery using few, fast-evolving proteins. This review details geminiviral invasion strategies and highlights knowledge gaps in their biology.
Area of Science:
- Plant pathology
- Virology
- Molecular biology
Background:
- Viruses are intracellular parasites that manipulate host cell machinery for replication.
- Geminiviruses cause significant crop diseases by targeting host proteins.
- These viruses encode a small number of multifunctional, rapidly evolving proteins.
Purpose of the Study:
- To provide an overview of geminiviral invasion steps in host plants.
- To explore current knowledge and identify unknowns in geminivirus biology.
Main Methods:
- Literature review of geminivirus-host interactions.
- Analysis of viral protein functions and host manipulation strategies.
- Synthesis of existing research on geminiviral infection cycles.
Main Results:
- Geminiviruses utilize a limited set of proteins to effectively re-wire plant development and physiology.
- Viral proteins target specific host factors to facilitate genome replication and spread.
- The interaction outcome is determined by the virus's success in manipulating the host.
Conclusions:
- Understanding geminivirus-host interactions is crucial for managing crop diseases.
- Further research is needed to fully elucidate the complexities of geminiviral invasion and replication.
- Identifying novel targets for antiviral strategies requires deeper knowledge of geminivirus biology.
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