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Protocol and Guidelines for Point-of-Care Lung Ultrasound in Diagnosing Neonatal Pulmonary Diseases Based on International Expert Consensus
Published on: March 6, 2019
[The chest x-ray in acute bronchiolitis: Technical quality, findings, and an assessment of its reliability]
Juan Manuel Rius Peris1, Ana Isabel Maraña Pérez1, Ana Valiente Armero2
1Hospital Virgen de la Luz, Cuenca, España; Instituto de Tecnología, Universidad de Castilla-La Mancha, Cuenca, España.
Insights
Chest x-rays are not reliable for diagnosing acute bronchiolitis (AB) in infants due to low observer agreement. This study found significant variability, making the diagnostic tool unreliable for infant AB assessment.
Area of Science:
- Pediatric Pulmonology
- Diagnostic Imaging
- Clinical Epidemiology
Background:
- Chest x-rays are frequently used for infant acute bronchiolitis (AB) despite clinical guidelines recommending against it.
- Reproducibility studies on chest x-ray interpretation in AB are limited.
- This study evaluates radiograph quality, findings, and inter-observer agreement in infant AB.
Purpose of the Study:
- To assess the inter-observer agreement of chest x-ray findings in infants diagnosed with acute bronchiolitis (AB).
- To evaluate the reliability of chest x-rays as a diagnostic tool for infant AB.
- To identify factors influencing the agreement among medical professionals interpreting infant chest x-rays.
Main Methods:
- 140 chest x-rays from 281 infants with AB were reviewed.
- Twelve physicians evaluated 10 predefined radiological signs.
- Inter-observer agreement was analyzed using Cohen's kappa (2 observers) and Fleiss' kappa (≥3 observers).
Main Results:
- Only 8.5% of radiographs indicated complicated AB.
- Medium agreement (kappa: 0.20-0.40) was observed among groups of 3+ observers.
- Wider variability (kappa: -0.20-0.60) was found between pairs of observers, influenced by the specific sign, medical specialty, and experience.
Conclusions:
- Low inter-observer agreement and high variability indicate chest x-rays are unreliable for infant AB assessment.
- The findings do not support the routine use of chest x-rays in managing infants with AB.
- Clinical practice guidelines should be reinforced regarding the non-recommendation of chest x-rays for infant AB.
Introduction:
Despite the recommendations of the current Clinical Practice Guidelines, the chest x-ray continues to be a widely used diagnostic test in the assessment of infants with acute bronchiolitis (AB). However, there have not been many studies that have assessed its reproducibility in these patients. In the present study, an evaluation is made on the radiographs, describing their quality, their radiological findings, and provides new evidence on the agreement between observers.
Method:
Out of a total of 281 infants admitted due to acute bronchiolitis, 140 chest x-rays were performed. Twelve doctors from different specialities evaluated the presence or absence of 10 radiological signs previously agreed by consensus. The level of agreement between 2 observers, and in groups of 3 or more, were analysed using the Cohen and Fleiss kappa index, respectively.
Results:
Only 8.5% of the radiographs showed evidence of a complicated AB. The between-observer agreement in groups of 3 or more was medium, and with little variability (kappa: 0.20-0.40). However, between 2 observers, each observer against radiologist, the variability was wider, (kappa: -0.20-0.60). This level of agreement was associated with factors including, the sign to evaluate, the medical specialty, and level of professional experience.
Conclusion:
The low levels of agreement between observers and the wide variability, makes the chest x-ray an unreliable diagnostic tool, and is not recommended for the assessment of infants with AB.
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