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Iatrogenic Cushing Syndrome And Hypertension In An Infant Girl Due To Use Of Nappy Rash Cream Containing A Potent
Saima Gillani1, Burhan Ali Danish1, Syed Faiz Muhammad Shah1
1Department of Paediatrics, Ayub Medical College, Abbottabad, Pakistan.
Journal of Ayub Medical College, Abbottabad : JAMC
|May 30, 2020
Summary
Topical steroid cream misuse in infants can lead to serious side effects. A potent steroid cream caused cushingoid features in an 11-month-old infant, highlighting the risks of prolonged use.
Area of Science:
- Pediatrics
- Dermatology
- Endocrinology
Background:
- Infant facial swelling prompted a pediatric visit.
- The child exhibited cushingoid facies, plethoric cheeks, and centripetal obesity.
Purpose of the Study:
- To identify the cause of cushingoid features in an infant.
- To highlight the risks associated with potent topical steroid use in children.
Main Methods:
- Clinical examination of an 11-month-old female infant.
- Review of patient history, including topical medication use.
- Assessment of physical signs and exclusion of other endocrine causes.
Main Results:
- The infant presented with cushingoid features and elevated blood pressure.
- Normal electrolyte and cortisol levels were observed.
- Prolonged use of a potent topical steroid (fluticasone) in a nappy rash cream was identified as the cause.
Conclusions:
- Potent topical steroids, like fluticasone, can cause systemic side effects in infants with prolonged use.
- Careful monitoring and parental education are crucial when prescribing topical steroids for pediatric conditions.
- Misuse of over-the-counter steroid creams can lead to iatrogenic Cushing's syndrome in infants.
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