Jove
Visualize
Contact Us

Related Concept Videos

Association Areas of the Cortex01:21

Association Areas of the Cortex

8.4K
Association areas are regions of the cerebral cortex that do not have a specific sensory or motor function. Instead, they integrate and interpret information from various sources to enable higher cognitive processes such as memory, learning, and decision-making. Some key association areas include the following:
Prefrontal Association Area: This area is located in the frontal lobe and is involved in planning, decision-making, and moderating social behavior. It connects with primary motor areas,...
8.4K
Neural Circuits01:25

Neural Circuits

2.5K
Neural circuits and neuronal pools are two of the main structures found in the nervous system. Neural circuits are networks of neurons that work together to carry out a specific task or process. They consist of interconnected neurons and glial cells, which provide structural and metabolic support.
Neuronal pools are collections of nerve cells with similar functions and interact through chemical and electrical signals. These pools include both interneurons (the central neural circuit nodes that...
2.5K
Somatosensory, Motor, and Association Cortex01:24

Somatosensory, Motor, and Association Cortex

1.9K
The somatosensory cortex in the parietal lobes is crucial for interpreting sensory data such as touch, temperature, and proprioception. The somatosensory cortex, situated in the parietal lobes, plays a vital role in interpreting sensory information like touch, temperature, and proprioception—awareness of body position. This specialized brain region features an organized structure wherein neurons at the top primarily process sensations originating from the lower body. In contrast, those at...
1.9K
Long-term Potentiation01:35

Long-term Potentiation

57.9K
Long-term potentiation, or LTP, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTP is the process of synaptic strengthening that occurs over time between pre- and postsynaptic neuronal connections. The synaptic strengthening of LTP works in opposition to the synaptic weakening of long-term depression (LTD) and together are the main mechanisms that underlie learning and memory.
57.9K
Long-term Potentiation01:25

Long-term Potentiation

3.2K
Long-term potentiation, or LTP, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTP is the process of synaptic strengthening that occurs over time between pre and postsynaptic neuronal connections. The synaptic strengthening of LTP works in opposition to the synaptic weakening of long-term depression (LTD) and together are the main mechanisms that underlie learning and memory.
Hebbian LTP
LTP can occur when...
3.2K
Motor and Sensory Areas of the Cortex01:14

Motor and Sensory Areas of the Cortex

6.5K
The cerebral cortex, the brain's outermost layer, is pivotal in processing complex cognitive tasks, emotions, and various sensory inputs and executing voluntary motor activities. This intricate structure is divided into three primary functional areas: the motor areas, sensory areas, and association areas.
Motor Areas
The motor areas located in the frontal lobe are central to controlling voluntary movements. This region is further subdivided into the primary motor cortex and the premotor cortex....
6.5K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Thalamic activation of the visual cortex at the single-synapse level.

Science (New York, N.Y.)·2026
Same author

Isotonic and minimally invasive optical clearing media for live cell imaging ex vivo and in vivo.

Nature methods·2026
Same author

Intermingled representation of oral cavity in mouse trigeminal ganglion.

Scientific reports·2025
Same author

Encoding of self-initiated actions in axon terminals of the mesocortical pathway.

Neurophotonics·2024
Same author

Functional Diversity of Dopamine Axons in Prefrontal Cortex During Classical Conditioning.

bioRxiv : the preprint server for biology·2023
Same author

A Canonical Scheme of Bottom-Up and Top-Down Information Flows in the Frontoparietal Network.

Frontiers in neural circuits·2021
Same journal

Transcriptomic and epigenetic characterization of paraventricular thalamic nucleus neurons in Polg1 mutant mice.

Neuroscience research·2026
Same journal

Modulation of the EEG alpha-band envelope during mental tasks: A task-related index based on second-order derivatives.

Neuroscience research·2026
Same journal

Enhanced calcium activity and transcriptomic alterations in iPSC-derived neurons from BAFME patients with repeat expansions.

Neuroscience research·2026
Same journal

Clustered protocadherinβs contribute to configuring functional cell populations in hippocampal-cortical regions.

Neuroscience research·2026
Same journal

ALS-associated protein TDP-43 disturbs axonal projections in the somatosensory cortex.

Neuroscience research·2026
Same journal

Microglial ontogeny and in vitro reconstruction: Bridging development and modeling.

Neuroscience research·2026
See all related articles
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: Dec 20, 2025

Statistical Modelling of Cortical Connectivity Using Non-invasive Electroencephalograms
08:51

Statistical Modelling of Cortical Connectivity Using Non-invasive Electroencephalograms

Published on: November 1, 2019

5.9K

Long-range connections enrich cortical computations.

Tatsuo K Sato1

  • 1Dept. of Physiology, Neuroscience Program, Biomedicine Discovery Inst., Monash University, Clayton, VIC 3800, Australia; PRESTO, Japan Science and Technology Agency, Saitama 332-0012, Japan.

Neuroscience Research
|May 30, 2020
PubMed
Summary
This summary is machine-generated.

Long-range connections in the cerebral cortex flexibly modulate neural processing for higher cognitive functions. Advanced techniques reveal their crucial roles in visual and hierarchical processing, with ongoing research into synaptic mechanisms.

Keywords:
Gain controlHierarchical processingLong-range connectivitySensory-Motor interactionSynaptic mechanismVisual cortex

More Related Videos

Double In Utero Electroporation to Target Temporally and Spatially Separated Cell Populations
10:45

Double In Utero Electroporation to Target Temporally and Spatially Separated Cell Populations

Published on: June 14, 2020

7.8K
A Computer-assisted Multi-electrode Patch-clamp System
11:01

A Computer-assisted Multi-electrode Patch-clamp System

Published on: October 18, 2013

14.4K

Related Experiment Videos

Last Updated: Dec 20, 2025

Statistical Modelling of Cortical Connectivity Using Non-invasive Electroencephalograms
08:51

Statistical Modelling of Cortical Connectivity Using Non-invasive Electroencephalograms

Published on: November 1, 2019

5.9K
Double In Utero Electroporation to Target Temporally and Spatially Separated Cell Populations
10:45

Double In Utero Electroporation to Target Temporally and Spatially Separated Cell Populations

Published on: June 14, 2020

7.8K
A Computer-assisted Multi-electrode Patch-clamp System
11:01

A Computer-assisted Multi-electrode Patch-clamp System

Published on: October 18, 2013

14.4K

Area of Science:

  • Neuroscience
  • Computational Neuroscience

Background:

  • The cerebral cortex performs complex computations for higher cognitive functions via local circuits and long-range connectivity.
  • Long-range connections dynamically modulate local processing, enhancing cortical flexibility.
  • Evidence suggests context-dependent effects of long-range connectivity, such as dual facilitatory and suppressive impacts in the visual cortex.

Purpose of the Study:

  • To review evidence on the essential roles of long-range connectivity in visual and hierarchical processing.
  • To explore the circuit and synaptic bases of long-range cortical connectivity.
  • To discuss challenges and recent technical advances in studying these synaptic mechanisms.

Main Methods:

  • Review of existing neuroscientific evidence.
  • Analysis of findings from optogenetics, anatomical tracing, and two-photon microscopy.
  • Discussion of computational models like divisive gain control.

Main Results:

  • Long-range connectivity plays crucial roles in visual and hierarchical processing across cortical areas.
  • The impact of long-range connections can be context-dependent, exhibiting dual facilitatory and suppressive effects.
  • Divisive gain control models can capture these dynamic modulations.

Conclusions:

  • Long-range connectivity is vital for flexible and sophisticated cortical computations.
  • Investigating the synaptic mechanisms of long-range connectivity is essential for understanding brain function.
  • Recent technological advancements are paving the way for deeper insights into these mechanisms.