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SnapShot: Ferroptosis
Kamyar Hadian1, Brent R Stockwell2
1Assay Development and Screening Platform, Helmholtz Zentrum Mu¨nchen, Neuherberg, Germany.
Cell
|May 30, 2020
Abstract:
Ferroptosis is a regulated form of cell death that occurs when phospholipids with polyunsaturated fatty acyl tails are oxidized in an iron-dependent manner. Research in recent years has uncovered complex cellular networks that induce and suppress lethal lipid peroxidation. This SnapShot provides an overview of ferroptosis-related pathways, including relevant biomolecules and small-molecule modulators regulating them.

