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Focal Dermal Elastosis: A Proposed Update to the Nomenclature
Maxwell Knapp1, Cari E Carpenter1, Katelyn Shea2
1The Robert Larner, M.D. College of Medicine at the University of Vermont, Burlington, VT.
The American Journal of Dermatopathology
|May 31, 2020
Summary
Late-onset focal dermal elastosis mimics other conditions but has no systemic links. This study proposes renaming it focal dermal elastosis to encompass a wider age range of affected individuals.
Area of Science:
- Dermatology
- Connective tissue disorders
Background:
- Late-onset focal dermal elastosis (LOFDE) is a rare skin condition.
- It clinically resembles pseudoxanthoma elasticum but lacks systemic manifestations.
- Previously, LOFDE was thought to affect only the elderly.
Observation:
- A case of a 59-year-old woman diagnosed with LOFDE is presented.
- This case highlights that the condition can occur in individuals younger than previously reported.
- The patient's presentation and diagnostic process are detailed.
Findings:
- LOFDE presents a diagnostic challenge due to its mimicry of other elastotic disorders.
- The condition's occurrence in a 59-year-old patient broadens the known age spectrum.
- Histopathological findings confirm the characteristic dermal elastosis.
Implications:
- The proposed term "focal dermal elastosis" better reflects the condition's broader age distribution.
- Accurate terminology is crucial for clinical recognition and research.
- Further studies are needed to understand the pathophysiology and long-term prognosis.
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