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Updated: Dec 20, 2025

Lethality Bioassay Using Artemia salina L.
Published on: October 11, 2022
Is stonefish Synanceia verrucosa envenomation potentially lethal?
C Maillaud1, T Hoang-Oppermann2, V Hoang-Oppermann2
1ISEA EA 7484, University of New Caledonia, P.O. Box R4, 98851, Noumea Cedex, New Caledonia.
Stonefish stings are rarely fatal, but this study highlights the severe cardiovascular risks of Synanceia verrucosa venom. Recent cases from New Caledonia and French Polynesia underscore its potentially lethal effects.
Area of Science:
- Marine toxicology
- Cardiovascular pathology
- Envenomation research
Background:
- Stonefish stings are infrequent causes of human fatality.
- Limited recent documentation exists on stonefish sting severity.
- Synanceia verrucosa is a venomous marine species.
Purpose of the Study:
- To document recent clinical cases of stonefish stings.
- To emphasize the cardiovascular toxicity of Synanceia verrucosa venom.
- To highlight the potentially lethal effects of stonefish envenomation.
Main Methods:
- Clinical case reporting.
- Analysis of patient data from New Caledonia and French Polynesia.
- Review of cardiovascular effects.
Main Results:
- Three clinical cases of stonefish stings were documented.
- One fatality occurred, linked to cardiovascular complications.
- Venom from Synanceia verrucosa demonstrated significant cardiovascular toxicity.
Conclusions:
- Stonefish stings, though rare, can be lethal.
- Cardiovascular toxicity is a primary concern in Synanceia verrucosa envenomation.
- Prompt medical attention is crucial for severe stonefish stings.
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