Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Acute Coronary Syndrome III: Diagnostic Studies01:30

Acute Coronary Syndrome III: Diagnostic Studies

9
Diagnosing acute coronary syndrome or ACS begins with a thorough patient history. Notable symptoms include central, crushing chest pain radiating to the left arm, neck, jaw, or back, along with shortness of breath, sweating (diaphoresis), nausea, vomiting, dizziness, and palpitations.It is crucial to note any history of cardiac illnesses and assess risk factors, including age, gender, smoking, hypertension, diabetes, hyperlipidemia, and a sedentary lifestyle.During physical examination, vital...
9
Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT01:25

Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT

29
Calcium-Scoring CT ScanA calcium-scoring CT scan, also known as coronary artery calcium (CAC) scan, detects calcium deposits in the coronary arteries. This test assesses the risk of coronary artery disease (CAD), which can lead to cardiovascular events such as angina, heart failure, and sudden cardiac arrest.A calcium-scoring CT scan is generally recommended for individuals at intermediate risk of CAD without symptoms. It includes:Men aged 40-75 and women aged 50-75: Especially those with a...
29
Imaging Studies for Cardiovascular System V: CT01:28

Imaging Studies for Cardiovascular System V: CT

31
Cardiac computed tomography (CT) scanning is an advanced cardiac imaging technique that utilizes CT technology, with or without intravenous (IV) contrast, to produce accurate cross-sectional virtual slices of specific areas of the heart, coronary circulation, and major blood vessels such as the aorta, pulmonary veins, and arteries. The computer processes these slices to generate three-dimensional images. Multidetector CT (MDCT) is a rapid form of CT scanning that captures multiple slices...
31
Imaging Studies for Cardiovascular System IV: CMRI01:21

Imaging Studies for Cardiovascular System IV: CMRI

49
Cardiovascular magnetic resonance imaging, or CMRI, is a non-invasive diagnostic test that employs a magnetic field and radiofrequency waves to create precise images of the heart and arteries. It provides comprehensive information about cardiac anatomy, function, perfusion, and tissue characterization without ionizing radiation.IndicationsCMRI diagnoses various heart conditions, including tissue damage from heart attacks, ischemic heart disease, myocarditis, aortic issues (tears, aneurysms,...
49
Computed Tomography01:10

Computed Tomography

4.6K
Tomography refers to imaging by sections. Computed tomography (CT) is a non-invasive imaging technique that uses computers to analyze several cross-sectional X-rays to reveal minute details about structures in the body.
The technique was invented in the 1970s and is based on the principle that as X-rays pass through the body, they are absorbed or reflected at different levels. In the technique, a patient lies on a motorized platform while a computerized axial tomography (CAT) scanner rotates...
4.6K
Imaging Studies VII: Vascular Imaging01:19

Imaging Studies VII: Vascular Imaging

15
DefinitionRenal angiography, also known as renal arteriography, is an imaging technique used to obtain a comprehensive view of blood flow and the vascular structure of blood vessels in the kidneys and surrounding areas.PurposeRenal angiography detects blood vessel abnormalities in the kidneys, such as aneurysms, stenosis, thrombosis, vascular tumors, and renal artery stenosis. It evaluates kidney function and guides interventional treatments like angioplasty or stent placement.Pre-Procedure...
15

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Integrating multimodal prehabilitation into enhanced recovery after surgery programs (MPhERAS) for elderly patients: a systematic review and meta-analysis of randomized controlled trials and cohort studies.

Techniques in coloproctology·2025
Same author

<i>Meso</i>-Modified Porphyrinoids: Stimuli-Driven Conformational Plasticity, Modulation of π-Conjugation, and Bis-Rh(I) Complexation.

Inorganic chemistry·2025
Same author

Nonalternant Acenaphthylene-Fused Carbaporphyrins: Topological Modulation of π-Delocalization, (Anti)aromaticity, and B<sup>III</sup> Coordination.

Organic letters·2025
Same author

Siamese Twin Homocarbaporphyrin Dimer: Nonplanar Architecture, Localized Conjugation and Bis-B<sup>III</sup> Complex.

Chemistry, an Asian journal·2025
Same author

<i>E</i>-Stilbene-Imprinted Cyclic Diphyrin and Its B<sup>III</sup> Complex.

Organic letters·2025
Same author

Ectopic expression of the cation-chloride cotransporter KCC2 in blood exosomes as a biomarker for functional rehabilitation.

Frontiers in molecular neuroscience·2025
Same journal

Direct Oral Anticoagulants versus Aspirin for Prevention of Overt and Covert Cerebral Infarction: A Meta-Analysis.

Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association·2026
Same journal

Efficacy of Pharyngeal Balloon Muscle Resistance Treatment in Post-Stroke Dysphagia: A Randomized Controlled Trial.

Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association·2026
Same journal

Detection of Atrial Fibrillation via Adhesive Single-Lead ECG vs. Holter Monitoring in Embolic Stroke of Undetermined Source: The AVANT-GARDE Trial.

Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association·2026
Same journal

Predictive Value of the Waist-to-Height Ratio and HbA1c Product for Incident Stroke: A Stratified Analysis by Blood Pressure Status.

Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association·2026
Same journal

Safety and efficacy of tirofiban as an adjunct to endovascular thrombectomy in large vessel occlusion stroke: A systematic review and meta-analysis with GRADE assessment.

Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association·2026
Same journal

Association of FVH/DWI mismatch with recanalization after mechanical thrombectomy in acute anterior-circulation large-vessel occlusion.

Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association·2026
See all related articles

Related Experiment Video

Updated: Jul 16, 2025

Optical Coherence Tomography Based Biomechanical Fluid-Structure Interaction Analysis of Coronary Atherosclerosis Progression
13:07

Optical Coherence Tomography Based Biomechanical Fluid-Structure Interaction Analysis of Coronary Atherosclerosis Progression

Published on: January 15, 2022

3.9K

CTP-based estimated ischemic core: A comparative multicenter study between Olea and RAPID software.

V Yedavalli1, S Kihira2, P Shahrouki2

  • 1Johns Hopkins University School of Medicine, Baltimore, MD, United States.

Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association
|September 22, 2023
PubMed
Summary
This summary is machine-generated.

CT perfusion (CTP) software shows significant variation in ischemic core volume estimation for large vessel occlusions. Both RAPID and Olea platforms correlate with final infarct volume, with low rates of overcalling large infarcts.

Keywords:
Acute ischemic strokeCT perfusionEndovascular thrombectomyLarge vessel occlusion

More Related Videos

Signal Acquisition, Score Interpretation, and Economics of a Non-Invasive Point-of-Care Test for Coronary Artery Disease
06:16

Signal Acquisition, Score Interpretation, and Economics of a Non-Invasive Point-of-Care Test for Coronary Artery Disease

Published on: August 9, 2024

448
Point of Care Transcranial Color-Coded Duplex Ultrasound of the Middle Cerebral Artery
04:01

Point of Care Transcranial Color-Coded Duplex Ultrasound of the Middle Cerebral Artery

Published on: August 9, 2024

762

Related Experiment Videos

Last Updated: Jul 16, 2025

Optical Coherence Tomography Based Biomechanical Fluid-Structure Interaction Analysis of Coronary Atherosclerosis Progression
13:07

Optical Coherence Tomography Based Biomechanical Fluid-Structure Interaction Analysis of Coronary Atherosclerosis Progression

Published on: January 15, 2022

3.9K
Signal Acquisition, Score Interpretation, and Economics of a Non-Invasive Point-of-Care Test for Coronary Artery Disease
06:16

Signal Acquisition, Score Interpretation, and Economics of a Non-Invasive Point-of-Care Test for Coronary Artery Disease

Published on: August 9, 2024

448
Point of Care Transcranial Color-Coded Duplex Ultrasound of the Middle Cerebral Artery
04:01

Point of Care Transcranial Color-Coded Duplex Ultrasound of the Middle Cerebral Artery

Published on: August 9, 2024

762

Area of Science:

  • Neuroimaging
  • Stroke Imaging
  • Cerebrovascular Disease

Background:

  • Cerebral perfusion tomography (CTP) is crucial for endovascular therapy (EVT) selection in large vessel occlusions (LVO).
  • Inconsistent ischemic core volume estimations exist between different CTP software packages.
  • This study compares CTP core volumes generated by RAPID and Olea software.

Purpose of the Study:

  • To compare CTP-estimated ischemic core volumes between RAPID and Olea software.
  • To assess the correlation of these estimations with final infarct volume (FIV) on MRI-DWI.
  • To evaluate software performance using heterogeneous data from multiple stroke centers.

Main Methods:

  • Retrospective analysis of 151 patients with anterior circulation LVO undergoing CTP and successful EVT.
  • Automated CTP analysis using Olea (rCBF < 25%, dTTP > 5s) and RAPID (rCBF < 30%).
  • Comparison of CTP-estimated core volumes with FIV on post-treatment MRI-DWI.

Main Results:

  • Significant differences in CTP-estimated ischemic core volumes between Olea (18.7 ± 18.9 mL) and RAPID (10.5 ± 17.9 mL) (p < 0.01).
  • Both software showed comparable, moderate correlation with FIV (r=0.38 for RAPID, r=0.39 for Olea).
  • Strong inter-software correlation (r=0.864, p < 0.001); low, identical rates of overcalling large cores (>70 mL).

Conclusions:

  • Substantial variation exists in CTP-estimated ischemic core volumes between Olea and RAPID software.
  • Both platforms demonstrate comparable correlation with final infarct volume.
  • Rates of overcalling large infarct volumes were low and similar for both software.