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Intellectual and developmental disability and COVID-19 case-fatality trends: TriNetX analysis
Margaret A Turk1, Scott D Landes2, Margaret K Formica3
1Department of Physical Medicine & Rehabilitation, SUNY Upstate Medical University, Syracuse, NY, 13210, USA.
COVID-19 poses a greater risk to individuals with intellectual and developmental disabilities (IDD), particularly younger age groups. While overall death rates were similar, age-stratified analysis reveals significant differences, highlighting the need for targeted research.
Area of Science:
- Public Health
- Epidemiology
- Disability Studies
Background:
- Limited reporting exists on COVID-19 trends for individuals with intellectual and developmental disabilities (IDD).
- People with IDD may face a higher risk of severe COVID-19 outcomes.
- Understanding these trends is crucial for public health interventions.
Purpose of the Study:
- To compare COVID-19 trends in individuals with and without IDD.
- To analyze trends stratified by age groups.
- To identify differences in comorbidities, case numbers, deaths, and case-fatality rates.
Main Methods:
- Utilized data from the TriNetX COVID-19 Research Network platform.
- Identified patients with a positive COVID-19 diagnosis up to May 14, 2020.
- Focused analysis on comorbidities, case counts, mortality, and case-fatality rates.
Main Results:
- Individuals with IDD exhibited a higher prevalence of comorbidities linked to poorer COVID-19 outcomes.
- Distinct age-related COVID-19 trends were observed in the IDD population, with more cases in younger individuals.
- Overall case-fatality rates were similar (5.1% IDD vs. 5.4% non-IDD), but varied significantly by age group.
Conclusions:
- COVID-19 presents a heightened risk for individuals with IDD, especially younger populations.
- Age-specific data reveals critical differences in COVID-19 impact on those with IDD.
- Further research is needed to document COVID-19 trends in people with IDD, focusing on age-related patterns.
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