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Updated: Dec 20, 2025

Tubal Cytology of the Fallopian Tube as a Promising Tool for Ovarian Cancer Early Detection
Published on: July 25, 2017
Primary transitional cell carcinoma of the fallopian tube: A case report and literature review
Dong-Hyun Lee1,2, Dong-Hyu Cho1,2, Kyoung Min Kim2,3
1Department of Obstetrics and Gynecology, Jeonbuk National University Hospital-Jeonbuk National University Medical School.
Introduction:
Primary transitional cell carcinoma (TCC) of the fallopian tube is an extremely rare tumor.
Patient Concerns:
A 79-year-old woman presenting with vaginal discharge.
Diagnosis:
Pelvic magnetic resonance imaging revealed a predominantly solid mass with a lobulated contour, measuring 5.5 cm × 4.6 cm, in the left ovary. The patient underwent total abdominal hysterectomy with bilateral salpingo-oophorectomy. Pathological analysis revealed a high-grade TCC, measuring 7.5 cm × 4 cm, in the left fallopian tube (International Federation of Gynecology and Obstetrics stage IIB).
Intervention:
Forty-three months postoperation, recurrence was diagnosed as peritoneal metastasis. The patient underwent 6 cycles of palliative chemotherapy consisting of cisplatin and gemcitabine, the recommended regimen for TCC of the urinary tract.
Outcome:
The patient has survived for 27 months without recurrence after palliative chemotherapy, 76 months after diagnosis.
Conclusion:
It is rare that primary TCC of the fallopian tube responds to a urinary tract treatment regimen for TCC, even when followed up for an extended period. More research is warranted to determine which treatment regimen will benefit patients the most.

