Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Peptidoglycan Synthesis01:28

Peptidoglycan Synthesis

1.6K
Structure of PeptidoglycanPeptidoglycan is a vital structural component of the bacterial cell wall, providing mechanical strength and shape to the cell. It consists of repeating units of two sugars—N-acetylglucosamine (NAG) and N-acetylmuramic acid (NAM)—linked by β-1,4 glycosidic bonds. These sugar chains are cross-linked by short peptide chains, forming a mesh-like polymer that surrounds the bacterial plasma membrane.Cytoplasmic Phase – Precursor SynthesisPeptidoglycan...
1.6K
Peptide Identification Using Tandem Mass Spectrometry01:33

Peptide Identification Using Tandem Mass Spectrometry

7.9K
Tandem mass spectrometry, also known as MS/MS or MS2, is an analytical technique that employs two mass analyzers. Essentially it is a series of mass spectrometers that helps isolate a particular biomolecule and then helps study its chemical properties.
This technique helps gather information regarding the protein from which the peptide was obtained and to study the peptides’ amino acid sequence. Identifying peptides from a complex mixture is an important component of the growing field of...
7.9K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Interface-Induced Concentration Enhancement in Glycine Solutions Investigated Using Surface Plasmon Resonance Spectroscopy and Molecular Dynamics Simulations.

The journal of physical chemistry letters·2026
Same author

Specific and non-specific interactions of fibronectin with zwitterionic peptoid brushes studied by molecular dynamics simulation.

Physical chemistry chemical physics : PCCP·2025
Same author

Characterising supramolecular gels: general discussion.

Faraday discussions·2025
Same author

Using supramolecular gels: general discussion.

Faraday discussions·2025
Same author

2D Interfacial Crystallization Stabilized by Short-Chain Aliphatic Interfaces.

Langmuir : the ACS journal of surfaces and colloids·2025
Same author

Martinoid: the peptoid martini force field.

Physical chemistry chemical physics : PCCP·2024

Related Experiment Video

Updated: Dec 20, 2025

Solid-phase Submonomer Synthesis of Peptoid Polymers and their Self-Assembly into Highly-Ordered Nanosheets
13:42

Solid-phase Submonomer Synthesis of Peptoid Polymers and their Self-Assembly into Highly-Ordered Nanosheets

Published on: November 2, 2011

29.9K

Peptoids for biomaterials science.

King Hang Aaron Lau1

  • 1Department of Pure and Applied Chemistry, University of Strathclyde, Thomas Graham Building, 295 Cathedral Street, Glasgow, G1 1XL, UK. aaron.lau@strath.ac.uk.

Biomaterials Science
|June 3, 2020
PubMed
Summary
This summary is machine-generated.

Poly(N-substituted glycine) peptoids are versatile for creating advanced biomaterials. Their unique self-assembled nanostructures and tunable properties offer new possibilities in biointerfaces and materials science.

More Related Videos

Synthesis and Mass Spectrometry Analysis of Oligo-peptoids
11:44

Synthesis and Mass Spectrometry Analysis of Oligo-peptoids

Published on: February 21, 2018

11.3K
Split-and-pool Synthesis and Characterization of Peptide Tertiary Amide Library
13:37

Split-and-pool Synthesis and Characterization of Peptide Tertiary Amide Library

Published on: June 20, 2014

18.6K

Related Experiment Videos

Last Updated: Dec 20, 2025

Solid-phase Submonomer Synthesis of Peptoid Polymers and their Self-Assembly into Highly-Ordered Nanosheets
13:42

Solid-phase Submonomer Synthesis of Peptoid Polymers and their Self-Assembly into Highly-Ordered Nanosheets

Published on: November 2, 2011

29.9K
Synthesis and Mass Spectrometry Analysis of Oligo-peptoids
11:44

Synthesis and Mass Spectrometry Analysis of Oligo-peptoids

Published on: February 21, 2018

11.3K
Split-and-pool Synthesis and Characterization of Peptide Tertiary Amide Library
13:37

Split-and-pool Synthesis and Characterization of Peptide Tertiary Amide Library

Published on: June 20, 2014

18.6K

Area of Science:

  • Materials Science
  • Biomaterials Science
  • Polymer Chemistry

Background:

  • Poly(N-substituted glycine) peptoids are peptide mimics with enhanced protease resistance and synthetic accessibility.
  • Conventionally used in drug discovery and therapeutics, peptoids offer unique structural and functional properties.
  • Recent advancements focus on their application in biomaterials science.

Purpose of the Study:

  • To review recent developments in peptoid self-assembled nanostructures.
  • To highlight the potential of peptoids in creating advanced macromolecular interfaces.
  • To showcase the versatility of peptoid design for biomaterials.

Main Methods:

  • Literature review of recent reports on peptoid self-assembly.
  • Analysis of peptoid nanostructures and their interface properties.
  • Exploration of peptoid synthesis strategies for biomaterials.

Main Results:

  • Peptoids form diverse self-assembled nanostructures.
  • Peptoid-based interfaces exhibit tunable properties for biomaterial applications.
  • Design flexibility allows for multifunctional biointerfaces.

Conclusions:

  • Peptoid self-assembly offers a powerful platform for novel biomaterials.
  • The modularity and tunability of peptoids are key for advanced biointerfaces.
  • Peptoid-based materials hold significant promise for future applications in materials science.