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Related Concept Videos

The Thyroid Gland01:23

The Thyroid Gland

6.4K
The thyroid gland is a small, butterfly-shaped gland located in the neck and covers the anterior surface of the trachea. The gland has two lateral lobes connected by a thin tissue mass called the isthmus. Internally, each lobe comprises many small spherical structures known as thyroid follicles, surrounded by a network of blood vessels.
The follicles have a central cavity lined by simple cuboidal to squamous epithelial cells called follicular cells. These cells produce the glycoprotein...
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Synthesis and Regulation of Thyroid Hormones01:20

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Low blood levels of the thyroid hormones — triiodothyronine (T3) and thyroxine (T4) — signal the hypothalamus to release the thyrotropin-releasing hormone (TRH). TRH then reaches the pituitary gland and stimulates the release of thyroid-stimulating hormone(TSH) into the bloodstream.
Upon reaching the thyroid gland, TSH stimulates the follicular cells' active uptake of iodide ions from the blood. The ions diffuse to the apical surface of the cells and are oxidized to iodine. The...
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Related Experiment Video

Updated: Dec 20, 2025

Minimal Invasive Resection of Large Retrosternal Thyroid Goiter
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Adequate thyroidectomy in laryngectomy.

Bipin T Varghese1, Deepak Janardhan1, Elizabeth Mathew Iype1

  • 1The Division of Head and Neck Surgery, Department of Surgical Services, Regional Cancer Centre, Trivandrum, Kerala, India.

Oral Oncology
|June 3, 2020
PubMed
Summary
This summary is machine-generated.

Optimal thyroid gland resection during laryngectomy is crucial for successful outcomes. This study proposes a concept for adequate removal of infiltrated thyroid tissue, drawing on literature and expert experience.

Keywords:
Adequate thyroidectomyClinical ExaminationCross sectional ImagingPer operative finding

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Area of Science:

  • Otolaryngology
  • Endocrinology
  • Surgical Oncology

Background:

  • Laryngectomy requires careful management of the thyroid gland for optimal results.
  • Thyroid gland involvement can complicate laryngectomy outcomes.

Discussion:

  • This work reviews current literature and presents expert experience on managing the thyroid gland during laryngectomy.
  • A proposed concept for adequate removal of infiltrated thyroid glandular tissue is detailed, irrespective of surgical setting or technique.

Key Insights:

  • Optimal thyroid resection is decisive for long-term functional and oncologic success in laryngectomy.
  • Adequate removal of infiltrated thyroid tissue is a key principle regardless of surgical approach.

Outlook:

  • Further research should focus on refining surgical techniques for thyroid management in laryngectomy.
  • Standardizing the approach to thyroid resection in laryngectomy could improve patient outcomes and reduce recurrence rates.