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Molecular Imaging of Cardiac Amyloidosis
Ahmad Masri1, Syed Bukhari2, Yvonne S Eisele2
1Division of Cardiology, Oregon Health and Science University, Portland, Oregon; and.
Abstract:
Transthyretin and light-chain amyloidosis are the 2 main causes of cardiac amyloidosis. Recent developments in molecular imaging have transformed our ability to diagnose transthyretin cardiac amyloidosis noninvasively and unmasked a hitherto unrecognized prevalence of the disease. This review summarizes the current and evolving imaging approaches, their molecular structural basis, and the gaps in imaging capabilities that have arisen as a result of parallel developments in pharmacotherapy delivering the first effective treatment options for this condition.
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