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Measurement of Tactile Allodynia in a Murine Model of Bacterial Prostatitis
Published on: January 16, 2013
Management of Chronic Bacterial Prostatitis
Zhuo Tony Su1, Jonathan Mark Zenilman2, Karen Sandell Sfanos1,3,4
1The James Buchanan Brady Urological Institute, Johns Hopkins University School of Medicine, 4940 Eastern Avenue, 301 Building, Suite 3112, Baltimore, MD, 21224, USA.
Chronic bacterial prostatitis often recurs after standard antibiotic treatment due to resistance. New therapies like bacteriophages show promise for difficult-to-treat cases.
Area of Science:
- Urology
- Infectious Diseases
- Microbiology
Background:
- Chronic bacterial prostatitis (CBP) presents significant management challenges.
- Recurrence of CBP after oral antimicrobial therapy is frequent.
Purpose of the Study:
- To review current literature on diagnosis and treatment of CBP.
- To highlight advanced and novel therapeutic strategies for refractory CBP.
Main Methods:
- Literature review of recent studies on CBP diagnosis and treatment.
- Analysis of conventional and emerging treatment modalities.
Main Results:
- Antimicrobial resistance and incomplete bacterial clearance contribute to CBP recurrence.
- Alternative treatments include fosfomycin, direct prostatic injections, surgery, and bacteriophages.
- Management of refractory CBP remains challenging, necessitating further research.
Conclusions:
- Novel therapeutic approaches are emerging for CBP refractory to conventional treatments.
- Further evidence is required to assess the efficacy and safety of these new modalities for chronic bacterial prostatitis.
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