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Targets and Combs: A Case of Lupus Enteritis
Mehdi Faraji1, Edgar Gutierrez2, Alex Glotser3
1Radiology, Louisiana State University Health Sciences Center, Shreveport, USA.
Cureus
|June 4, 2020
Summary
Lupus enteritis, a rare gastrointestinal complication of lupus, presents with specific imaging signs but requires comprehensive evaluation. Prompt diagnosis and immunosuppressant treatment can reverse symptoms, though recurrence is possible.
Area of Science:
- Rheumatology
- Gastroenterology
- Radiology
Background:
- Lupus is a systemic autoimmune disease affecting multiple organs.
- Lupus enteritis is a rare gastrointestinal manifestation.
- Gastrointestinal symptoms prompt investigation for lupus enteritis.
Observation:
- Diagnosis of lupus enteritis relies on imaging findings like bowel wall edema (target sign) and vascular engorgement (comb sign) on CT scans.
- These imaging findings are nonspecific and can indicate other causes of bowel wall ischemia.
- Lupus enteritis requires differentiation from other conditions causing similar radiological signs.
Findings:
- The presented case involved a lupus patient diagnosed with lupus enteritis via imaging.
- Treatment with immunosuppressants led to the resolution of the patient's symptoms.
- The case underscores the importance of a multimodal diagnostic approach.
Implications:
- Early and accurate diagnosis of lupus enteritis is crucial for effective management.
- Immunosuppressive therapy is the primary treatment for lupus enteritis.
- Multidisciplinary evaluation including physical exams, laboratory tests, and imaging is essential for optimal patient outcomes and to rule out complications like perforation.

