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Nanomaterial-based multiplex optical sensors.

Xiaojing Pei1, Guangyu Tao, Xi Wu

  • 1College of Chemistry and Materials Engineering, Beijing Technology and Business University, Beijing 100048, P. R. China.

The Analyst
|June 4, 2020
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Summary
This summary is machine-generated.

This review highlights nanomaterial-based optical multiplex sensors for simultaneous analysis. These advanced nanoprobes offer high accuracy and efficiency for biomedical research and clinical diagnostics.

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Area of Science:

  • Biomedical Engineering
  • Nanotechnology
  • Analytical Chemistry

Background:

  • Multiplexed bioassays are crucial for simultaneous analysis in biomedical research and clinical diagnostics.
  • Nanotechnology advancements have enabled the development of innovative multiplex optical bioassays.
  • Nanomaterials offer unique properties like tunable size, large surface-to-volume ratio, and efficient signal transduction.

Purpose of the Study:

  • To summarize recent advancements (last 5 years) in nanomaterial-based optical multiplex sensors.
  • To review various optical techniques utilized in these sensors.
  • To provide fundamentals and examples of their applications.

Main Methods:

  • Review of scientific literature focusing on nanomaterial-based optical multiplex sensors.
  • Categorization of sensors based on optical techniques: fluorescence, SERS, LSPR, CL.
  • Inclusion of multimodal approaches combining different techniques.

Main Results:

  • Nanomaterials are key components in fabricating novel optical nanoprobes.
  • Diverse optical techniques are employed for sensitive and efficient multiplex detection.
  • Multimodality offers enhanced capabilities for complex biological analyses.

Conclusions:

  • Nanomaterial-based optical multiplex sensors represent a significant advancement in bioanalysis.
  • These sensors provide high throughput, accuracy, and efficiency for biomedical and clinical applications.
  • Continued development in nanotechnologies promises further innovation in multiplex sensing.