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Neurological complications in patients with SARS-CoV-2 infection: a systematic review
Renato Puppi Munhoz1, José Luiz Pedroso2, Fábio Augusto Nascimento3
1Movement Disorders Centre, Toronto Western Hospital, University of Toronto, Toronto, ON, Canada.
Background:
As the COVID-19 pandemic unfolds worldwide, different forms of reports have described its neurologic manifestations.
Objective:
To review the literature on neurological complications of SARS-CoV-2 infection.
Methods:
Literature search performed following systematic reviews guidelines, using specific keywords based on the COVID-19 neurological complications described up to May 10th, 2020.
Results:
A total of 43 articles were selected, including data ranging from common, non-specific symptoms, such as hyposmia and myalgia, to more complex and life-threatening conditions, such as cerebrovascular diseases, encephalopathies, and Guillain-Barré syndrome.
Conclusion:
Recognition of neurological manifestations of SARS-CoV-2 should be emphasized despite the obvious challenges faced by clinicians caring for critical patients who are often sedated and presenting other concurrent systemic complications.
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