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Published on: May 1, 2019
Gastric adenocarcinoma appearance in leiomyoma: A case report
Kaoru Wada1, Hirofumi Tazawa2, Toshiaki Komo2
1Department of Internal Medicine, National Hospital Organization, Kure Medical Center, Chugoku Cancer Center, 3-1 Aoyama, Kure City, Hiroshima, 737-0023, Japan.
Introduction:
We experienced an extremely rare case of gastric adenocarcinoma wrapped by leiomyoma.
Presentation Of Case:
A 65-year-old man had an abnormality (filling defect) of the upper gastrointestinal series in his first medical checkup five years prior. Esophagogastroduodenoscopy detected a 10 mm submucosal tumor-like lesion in the greater curvature of the upper gastric remnant body. Despite repeated biopsy from the lesion, there was no sign of malignancy. A delle was observed on the top of the tumor at another visit five year after the first and a biopsy specimen revealed poorly differentiated adenocarcinoma. Therefore, laparoscopic gastrectomy was performed. Histological assessment revealed a 28 × 22 mm elevated lesion with a slight depression. Microscopically, papillary adenocarcinoma was observed at the submucosa with a solitary heterotopic gastric gland adjacent to the lesion. The final diagnosis was papillary adenocarcinoma arising from a solitary heterotopic gastric gland in the leiomyoma. No recurrence has occurred during a follow-up of two and a half years after surgery.
Conclusions:
This is the first report of gastric adenocarcinoma arising from a submucosal tumor.
