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Related Concept Videos

Cranial and Spinal Meninges01:19

Cranial and Spinal Meninges

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The cranial and spinal meninges are complex protective structures surrounding the central nervous system (CNS), consisting of the brain and spinal cord. These meninges consist of the dura mater, the arachnoid mater, and the pia mater. They protect the CNS, provide structural support, and aid in circulating cerebrospinal fluid (CSF).
Cranial Meninges
These meningeal layers cover the cranium. The dura mater is the outermost layer of cranial meninges. It is a thick and durable membrane of dense...
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Related Experiment Video

Updated: Dec 19, 2025

Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery
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Parasellar Meningiomas.

Thomas Graillon1,2, Jean Regis3, Anne Barlier4,5

  • 1Neurosurgery Department, Aix-Marseille University, Assistance Publique-Hôpitaux de Marseille, CHU Timone, Marseille, France, Thomas.Graillon@ap-hm.fr.

Neuroendocrinology
|June 4, 2020
PubMed
Summary
This summary is machine-generated.

Parasellar meningiomas are typically benign WHO grade I tumors. Management ranges from observation for asymptomatic cases to surgery or radiosurgery for growing or aggressive tumors, with a case-by-case approach recommended.

Keywords:
DiagnosisMeningiomaParasellar spacesSurgeryTherapy

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Area of Science:

  • Neurosurgery
  • Neuro-oncology
  • Skull Base Surgery

Background:

  • Parasellar spaces house critical neurovascular structures.
  • Meningiomas are the most common tumors in this region, often benign (WHO grade I).
  • Management strategies depend on tumor characteristics and symptoms.

Purpose of the Study:

  • To review the diagnosis and management of parasellar meningiomas.
  • To discuss surgical and non-surgical treatment options.
  • To highlight potential complications and long-term follow-up.

Main Methods:

  • Review of current literature on parasellar meningiomas.
  • Discussion of diagnostic criteria and treatment modalities.
  • Analysis of surgical approaches and adjuvant therapies.

Main Results:

  • Benign meningiomas (WHO grade I) are prevalent.
  • Conservative management or observation is suitable for asymptomatic tumors.
  • Surgery, radiosurgery, and other therapies are employed based on tumor size, location, and aggressiveness.
  • Potential complications include vascular injury, CSF leakage, and neurological deficits.

Conclusions:

  • Parasellar meningiomas require individualized treatment plans.
  • Complete resection is often challenging, necessitating long-term surveillance.
  • Multimodal treatment strategies, including radiosurgery and targeted therapies, are crucial for managing complex cases.