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Florida research open-source synchronization tool (FROST) for electrophysiology experiments
Jose D Alcantara1, Robert S Eisinger2, Enrico Opri1
1J. Crayton Pruitt Department of Biomedical Engineering, University of Florida, Gainesville, FL, United States.
Journal of Neuroscience Methods
|June 5, 2020
Summary
Researchers developed an affordable, open-source synchronization tool called FROST to precisely time electrophysiological data acquisition. This device integrates various experimental hardware, enhancing data accuracy in cognitive and behavioral studies.
Area of Science:
- Neuroscience
- Biomedical Engineering
- Computer Science
Background:
- Accurate interpretation of electrophysiological data is crucial for cognitive and behavioral research.
- Time-stamping experimental events, like stimulus presentation, is essential for data integrity.
Purpose of the Study:
- To introduce an inexpensive, open-source hardware and firmware solution for synchronizing diverse peripheral devices in electrophysiological research.
- To provide a customizable platform for integrating novel sensors and improving experimental timing accuracy.
Main Methods:
- Developed the Florida Research Open-source Synchronization Tool (FROST), a ∼30 USD central relay device.
- Designed FROST with adaptable hardware and Arduino-based firmware for easy modification and sensor integration.
- Demonstrated FROST's application in human intracranial and surface electroencephalography (EEG) recordings, and in a rodent experiment.
Main Results:
- FROST successfully synchronized multiple peripheral devices, including stimulus presentation screens, response buttons, and physiological sensors.
- Timing delays of the FROST device were characterized and demonstrated.
- The device proved adaptable for various experimental setups, including human and animal research.
Conclusions:
- FROST offers a cost-effective and customizable solution for synchronizing electrophysiological data acquisition.
- The open-source nature of FROST promotes widespread adoption and replication in research.
- This tool addresses the current scarcity of adaptable open-source synchronization solutions in the field.
