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IridiumIII Luminescent Probe for Detection of the Malarial Protein Biomarker Histidine Rich Protein-II
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Dual-emission CdTe quantum dot@ZIF-365 ratiometric fluorescent sensor and application for highly sensitive detection
Xing Ze Wang1, Zi Qing Zhang1, Rui Guo1
1Key Laboratory of Inorganic-Organic Hybrid Functional Material Chemistry (Tianjin Normal University), Ministry of Education, Tianjin Key Laboratory of Structure and Performance for Functional Molecule, College of Chemistry, Tianjin Normal University, 393 Binshui West Road, Tianjin, 300387, PR China.
Insights
A novel CdTe@ZIF-365 material serves as a dual-emission sensor for detecting l-histidine and copper ions (Cu2+). This advancement offers sensitive and selective detection for environmental and industrial monitoring.
Area of Science:
- Materials Science
- Environmental Science
- Analytical Chemistry
Background:
- l-histidine is a semi-essential amino acid with medical uses but risks from overuse, including environmental pollution.
- Copper ion (Cu2+) pollution is a persistent environmental concern due to its accumulation and migration characteristics.
Purpose of the Study:
- To synthesize a novel dual-emission hybrid material, CdTe@ZIF-365, for sensing applications.
- To develop a highly sensitive and selective ratiometric fluorescent sensor for both l-histidine and Cu2+.
Main Methods:
- Post-synthesis strategy to incorporate Cadmium Telluride (CdTe) quantum dots into Zeolitic Imidazolate Framework-365 (ZIF-365).
- Utilized Transmission Electron Microscopy (TEM) and N2 absorption tests to characterize the hybrid material.
- Employed the CdTe@ZIF-365 material as a bi-functional ratiometric fluorescent sensor.
Main Results:
- Successfully synthesized CdTe@ZIF-365 with high quantum yield.
- Demonstrated high sensitivity and selectivity for Cu2+ detection (Ksv = 2.7417 × 10^7 M⁻¹).
- Achieved excellent sensitivity and selectivity for l-histidine detection (Ksv = 6.0507 × 10^8 M⁻¹).
Conclusions:
- CdTe@ZIF-365 is the first reported material for dual ratiometric fluorescent sensing of l-histidine and Cu2+.
- The developed sensor shows significant potential for environmental monitoring and industrial applications.
- This hybrid material offers a promising platform for sensitive and selective analyte detection.
Abstract:
l-histidine acts as a semi-essential amino acid, which is medically used in the treatment of gastric ulcer, anemia, allergies. However, the overuse of l-histidine will result in terrible damage to heart disease, slow growth of animals and water pollution in the environment. In addition, Cu2+ pollution is common environmental pollution in the industry. It has the characteristics of high accumulation, migration, and persistence. Given this, through the post-synthesis strategy, CdTe quantum dots (QDs) were the first time to introduce into zeolitic imidazolate framework-ZIF-365 to synthesis dual-emission hybrid material CdTe@ZIF-365 with high quantum yield. TEM mappings and N2 absorption tests are applied to confirm the combination mode between CdTe quantum dots and ZIF-365. It should be noted that CdTe@ZIF-365 can be successfully utilized as a bi-functional ratiometric sensor for highly sensitive discrimination of l-histidine and Cu2+. Firstly, CdTe@ZIF-365 is applied to a fluorescent ratiometric sensor for Cu2+ with high sensitivity (the Ksv value is 2.7417✕107 [M-1]) and selectivity in the mixed cation ions' solution. On the other hand, CdTe@ZIF-365 also behaved as the first example for an excellent ratiometric fluorescent senor for l-histidine with high sensitivity (the Ksv value is 6.0507✕108 [M-1]) and selectivity in the mixed amino acids' solutions.
