Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Modern Molecular Taxonomy01:29

Modern Molecular Taxonomy

473
Advancements in molecular biology have revolutionized the identification and characterization of bacteria, with multiple methods leveraging DNA sequencing for enhanced precision. As sequencing technologies improve and costs decline, these approaches are increasingly used in clinical, environmental, and evolutionary studies.Multilocus Sequence Typing (MLST) examines several housekeeping genes, essential chromosomal genes encoding cellular functions, to distinguish strains. Approximately...
473
Genomic DNA in Eukaryotes00:58

Genomic DNA in Eukaryotes

51.9K
Eukaryotes have large genomes compared to prokaryotes. To fit their genomes into a cell, eukaryotic DNA is packaged extraordinarily tightly inside the nucleus. To achieve this, DNA is tightly wound around proteins called histones, which are packaged into nucleosomes that are joined by linker DNA and coil into chromatin fibers. Additional fibrous proteins further compact the chromatin, which is recognizable as chromosomes during certain phases of cell division.
51.9K
Animal Mitochondrial Genetics02:59

Animal Mitochondrial Genetics

8.8K
Among all the organelles in an animal cell, only mitochondria have their own independent genomes. Animal mitochondrial DNA is a double-stranded, closed-circular molecule with around 20,000 base pairs. Mitochondrial DNA is unique in that one of its two strands, the heavy, or H, -strand is guanine rich, whereas the complementary strand is cytosine rich and called the light, or L, -strand. Compared to nuclear DNA, mitochondrial DNA has a very low percentage of non-coding regions and is marked by...
8.8K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Insights into TNXB-Related Classical-Like Ehlers-Danlos Syndrome: A Study of Polish Patients.

Open access rheumatology : research and reviews·2026
Same author

Human NT2/D1-derived early neural progenitor cells immobilised in alginate microfibres as an <i>in vitro</i> 3D system for neurotoxicity testing.

Alternatives to laboratory animals : ATLA·2026
Same author

Continent-wide differentiation of fitness traits and patterns of climate adaptation among European populations of <i>Drosophila melanogaster</i>.

Evolution letters·2025
Same author

Oral microbiome dynamics in Postmortem Interval estimation: research standards and guidelines.

Archiwum medycyny sadowej i kryminologii·2025
Same author

Towards Genetically Informed Conservation of the Bardoka and Karakachan Sheep Breeds Autochthonous to Serbia.

Animals : an open access journal from MDPI·2025
Same author

Methodology for the analysis of biological impurities associated with peri-eucharistic phenomena.

Applied microbiology and biotechnology·2025

Related Experiment Video

Updated: Dec 19, 2025

Author Spotlight: Transmitochondrial Cybrid Generation Using Cancer Cell Lines
07:49

Author Spotlight: Transmitochondrial Cybrid Generation Using Cancer Cell Lines

Published on: March 17, 2023

3.0K

Complete mitogenome data for the Serbian population: the contribution to high-quality forensic databases.

Slobodan Davidovic1,2, Boris Malyarchuk3, Tomasz Grzybowski4

  • 1Institute of Molecular Genetics and Genetic Engineering, University of Belgrade, PO Box 23, Vojvode Stepe 444a, Belgrade, 11010, Serbia.

International Journal of Legal Medicine
|June 7, 2020
PubMed
Summary

Mitochondrial genome (mtDNA) data for 226 Serbians were analyzed, revealing high genetic diversity and unique maternal lineages. This research enhances forensic casework by providing crucial reference data for South Slavic populations.

Keywords:
Complete mitogenomesDemographic changesMolecular phylogeographySerbian population

More Related Videos

Author Spotlight: High-Throughput Image-Based Quantification of Mitochondrial DNA Synthesis and Distribution
10:47

Author Spotlight: High-Throughput Image-Based Quantification of Mitochondrial DNA Synthesis and Distribution

Published on: May 5, 2023

4.2K
Application of DNA Fingerprinting using the D1S80 Locus in Lab Classes
08:35

Application of DNA Fingerprinting using the D1S80 Locus in Lab Classes

Published on: July 17, 2021

22.6K

Related Experiment Videos

Last Updated: Dec 19, 2025

Author Spotlight: Transmitochondrial Cybrid Generation Using Cancer Cell Lines
07:49

Author Spotlight: Transmitochondrial Cybrid Generation Using Cancer Cell Lines

Published on: March 17, 2023

3.0K
Author Spotlight: High-Throughput Image-Based Quantification of Mitochondrial DNA Synthesis and Distribution
10:47

Author Spotlight: High-Throughput Image-Based Quantification of Mitochondrial DNA Synthesis and Distribution

Published on: May 5, 2023

4.2K
Application of DNA Fingerprinting using the D1S80 Locus in Lab Classes
08:35

Application of DNA Fingerprinting using the D1S80 Locus in Lab Classes

Published on: July 17, 2021

22.6K

Area of Science:

  • Forensic genetics
  • Population genetics
  • Mitochondrial DNA analysis

Background:

  • Mitochondrial genomes (mtDNA) are vital for human forensic casework due to their high discriminatory power.
  • Current reference databases lack comprehensive mtDNA data for South Slavic populations, particularly Serbians.

Purpose of the Study:

  • To generate and analyze complete mitochondrial genome data for 226 Serbian individuals.
  • To expand the reference database for South Slavic populations in forensic genetics.
  • To investigate the genetic diversity and phylogenetic position of the Serbian population within Europe.

Main Methods:

  • High-resolution sequencing of complete mitochondrial genomes (mtDNA).
  • Phylogenetic analysis and Bayesian skyline analysis.
  • Population genetic comparisons with ten other European populations.

Main Results:

  • Identification of 143 (sub)haplogroups, predominantly West Eurasian.
  • High percentage of unique haplotypes (85%) and low random match probability (0.53%).
  • Evidence of pronounced genetic differentiation from other Slavic populations and population expansion post-Last Glacial Maximum.

Conclusions:

  • The generated Serbian mtDNA data significantly enhances forensic reference databases for South Slavs.
  • The study confirms high genetic diversity in Serbians and refines understanding of European population history.
  • High-resolution mtDNA data improves the interpretation of forensic casework globally.