Related Experiment Video
Updated: Dec 19, 2025

Esophageal Heat Transfer for Patient Temperature Control and Targeted Temperature Management
Published on: November 21, 2017
Therapeutic Temperature Modulation for a Critically Ill Patient with COVID-19
Han Gil Jeong1, Yunghee Lee2, Kyoung Ho Song3
1Division of Neurocritical Care, Department of Neurosurgery and Neurology, Seoul National University Bundang Hospital, Seongnam, Korea.
Therapeutic temperature modulation effectively managed hyperpyrexia in a severe COVID-19 patient with cytokine storm syndrome. This intervention improved oxygenation and shock, potentially reducing the need for extracorporeal membrane oxygenation.
Area of Science:
- Critical Care Medicine
- Infectious Diseases
- Physiology
Background:
- Cytokine storm syndrome is a severe complication of COVID-19, leading to hyperpyrexia, shock, and acute respiratory distress syndrome.
- High fever (hyperpyrexia) increases metabolic demand and exacerbates inflammation, potentially worsening outcomes in critically ill patients.
- Extracorporeal membrane oxygenation (ECMO) is a life-saving but resource-intensive intervention for refractory cases.
More Related Videos
Related Concept Videos
Decreased Body Temperature
Increased Body Temperature
Methods of reducing fever
Pharmacological Methods of Reducing Fever:
Factors Affecting Body Temperature
Factors may include:
Homeostatic Imbalances in Body Temperature
Assessing Body Temperature - Rectal
Follow these steps for rectal temperature assessment:
Step 1: Perform hand hygiene and don clean gloves to prevent cross-infection.
Step 2: Position the patient in a side-lying position to better visualize the rectal...

