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Updated: Dec 19, 2025

Visualizing Cellular Gibberellin Levels Using the nlsGPS1 Förster Resonance Energy Transfer (FRET) Biosensor
Published on: January 12, 2019
Gibberellin Metabolism in Flowering Plants: An Update and Perspectives
Juan He1,2, Peiyong Xin1, Xueting Ma1,2
1State Key Laboratory of Plant Genomics and National Center for Plant Gene Research, Institute of Genetics and Developmental Biology, The Innovative Academy of Seed Design, Chinese Academy of Sciences, Beijing, China.
Abstract:
In plants, gibberellins (GAs) play important roles in regulating growth and development. Early studies revealed the large chemodiversity of gibberellins in plants, but only GA1, GA3, GA4, and GA7 show biological activity that controls plant development. However, the elucidation of the GA metabolic network at the molecular level has lagged far behind the chemical discovery of GAs. Recent advances in downstream GA biosynthesis (after GA12 formation) suggest that species-specific gibberellin modifications were acquired during flowering plant evolution. Here, we summarize the current knowledge of GA metabolism in flowering plants and the physiological functions of GA deactivation, with a focus on GA 13 hydroxylation. The potential applications of GA synthetic biology for plant development are also discussed.
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