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Isolated Ocular Sarcoidosis Mimicking Ring Melanoma
Carsten Faber1, Rasmus Ejstrup1, Karine Madsen2
1Department of Ophthalmology, University Hospital Copenhagen, Rigshospitalet, Copenhagen, Denmark.
Ocular Oncology and Pathology
|June 9, 2020
Summary
Isolated ocular sarcoidosis can mimic ring melanoma, a rare eye tumor. Biopsy is crucial before enucleation to avoid misdiagnosis and ensure correct treatment for this ciliary body mass.
Area of Science:
- Ophthalmology
- Pathology
Background:
- Ciliary body tumors can present diagnostic challenges.
- Melanoma is a common intraocular malignancy requiring prompt treatment.
- Ocular sarcoidosis is a rare inflammatory condition affecting the eye.
Observation:
- A young female presented with a large ciliary body tumor mimicking melanoma.
- Preoperative imaging (ultrasound biomicroscopy, MRI) and scleral transillumination suggested melanoma.
- Systemic work-up for malignancy was negative.
Findings:
- Perioperative frozen section revealed granulomatous inflammation, not melanoma.
- The tumor resolved completely after a subtenon injection of triamcinolone.
- The clinical presentation and response to treatment met criteria for isolated ocular sarcoidosis.
Implications:
- Ocular sarcoidosis can present with clinical features indistinguishable from ring melanoma.
- Biopsy is essential for accurate diagnosis of ciliary body masses before considering enucleation.
- Early diagnosis and appropriate treatment of ocular sarcoidosis can prevent unnecessary radical surgery.
