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Application of Laparoscopic Hepatectomy Combined with Intraoperative Microwave Ablation in Colorectal Cancer Liver Metastasis
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Application of Laparoscopic Hepatectomy Combined with Intraoperative Microwave Ablation in Colorectal Cancer Liver Metastasis

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Could hepatic ablation promote development of colon cancer hepatic metastases?

Crystal Kyaw1, Joyce Wong2

  • 1Department of Surgery, Lenox Hill Hospital at Northwell Health, New York, NY 10075, USA.

Hepatobiliary Surgery and Nutrition
|June 9, 2020
PubMed
Abstract

No abstract available in PubMed .

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In pharmacotherapy, monitoring drug concentrations is paramount, especially for drugs whose therapeutic effects hinge on both the active compound and its metabolite. Hepatic impairment profoundly influences drug potency by altering liver function. If the drug is more potent than its metabolite, impaired liver function amplifies drug activity due to elevated drug concentration levels. Conversely, if the metabolite holds greater potency, diminished liver function diminishes drug activity by...
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