Related Experiment Videos
Commentary to "Linear and Nonlinear System Approaches in Pharmacokinetics. How much do they have to offer? I. General
1Drug Metabolism Department, Merrell Dow Research Institute, Cincinnati, Ohio 45215-6300.
Abstract
No abstract available in PubMed .
Related Concept Videos
Articles linked to this work by shared authors, journal, and citation graph.
Pharmacokinetic determinants in the design and evaluation of sustained-release dosage forms.
Pharmaceutical research·2013
Human in vivo competitive inhibition of P450 substrates: increased plasma concentrations as a function of hepatic extraction ratio and percent inhibition.
Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques·2000
Cytochrome P450 3A4 in vivo ketoconazole competitive inhibition: determination of Ki and dangers associated with high clearance drugs in general.
Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques·2000
Estimation of Ki in a competitive enzyme-inhibition model: comparisons among three methods of data analysis.
Drug metabolism and disposition: the biological fate of chemicals·1999
First-time-in-human dose selection: allometric thoughts and perspectives.
Journal of clinical pharmacology·1995
Human dolasetron pharmacokinetics: II. Absorption and disposition following single-dose oral administration to normal male subjects.
Biopharmaceutics & drug disposition·1993
Integrated equation to evaluate accumulation profiles of drugs eliminated by Michaelis-Menten kinetics.
Journal of pharmacokinetics and biopharmaceutics·2010
Applications of a recirculatory stochastic pharmacokinetic model: limitations of compartmental models.
Journal of pharmacokinetics and biopharmaceutics·2010
Effect of plasma protein and tissue binding on the time course of drug concentration in plasma.
Journal of pharmacokinetics and biopharmaceutics·2010
Pharmacokinetics of methotrexate in solid tumors.
Journal of pharmacokinetics and biopharmaceutics·2010
Single- and multiple-dose kinetics of oral lorazepam in humans: the predictability of accumulation.
Journal of pharmacokinetics and biopharmaceutics·2010
Comparison of the in vitro and in vivo release of digoxin from four different soft gelatin capsule formulations.
Journal of pharmacokinetics and biopharmaceutics·2010
Complete characterization of anisotropic geodesics in the Euclidean space.
Geometriae dedicata·2026
A General Nonuniqueness Result for Yamabe-Type Problems for Conformally Variational Riemannian Invariants.
Journal of geometric analysis·2026
Universal Nonpower Law Scaling from a Chaotic Renormalization Group in the Harper-Hofstadter Model.
Physical review letters·2026
Generalized Fiducial Inference on Differentiable Manifolds.
International journal of approximate reasoning : official publication of the North American Fuzzy Information Processing Society·2026
Holographic Origin of a Maximization and Higher-Derivative AdS_{5}/CFT_{4}.
Physical review letters·2026