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Updated: Dec 19, 2025

A Simple and Efficient Approach to Construct Mutant Vaccinia Virus Vectors
Published on: October 30, 2016
Potential for gene editing in antiviral resistance
Douglas Euan Pyott1, Yue Fei1, Attila Molnar1
1The University of Edinburgh, Institute of Molecular Plant Sciences, Mayfield Road, Edinburgh, EH9 3BF, United Kingdom.
Abstract:
The discovery of CRISPR/Cas systems and their subsequent application in genome modifications and in gene expression control have fundamentally changed both basic and applied research. They have already been employed to generate novel virus resistance traits either by modifying host factors in the plant genome or by directly inducing targeted virus degradation. Here we summarise the latest developments in this field and discuss the potential applications and concerns around this technology.
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