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Published on: September 26, 2018
Heart rate as a predictor of cardiovascular risk
Gino Seravalle1, Fosca Quarti Trevano2, Guido Grassi2
1Department of Cardiology, Italian Auxological Institute S. Luca Hospital, Milan, Italy - g_seravalle@yahoo.com.
Insights
Resting heart rate is an easily measured indicator. Elevated resting heart rate is linked to increased cardiovascular disease risk, informing treatment strategies.
Area of Science:
- Cardiology
- Clinical Physiology
Background:
- Resting heart rate (RHR) is a readily measurable physiological parameter.
- Evidence links elevated RHR to adverse cardiovascular outcomes in prospective studies and meta-analyses.
- Understanding RHR control and dysfunction is crucial for risk assessment.
Purpose of the Study:
- To review the role of resting heart rate as a predictor of cardiovascular risk.
- To provide insights into non-pharmacological and pharmacological treatments for cardiovascular risk reduction.
Main Methods:
- Literature review of prospective studies and meta-analyses.
- Analysis of physiological and pathophysiological mechanisms of heart rate control.
- Identification of normal cut-off values for RHR.
Main Results:
- Elevated resting heart rate is associated with increased cardiovascular disease and mortality.
- Knowledge of RHR mechanisms aids in defining normal ranges.
- RHR serves as a valuable prognostic indicator.
Conclusions:
- Resting heart rate is a significant, easily assessed predictor of cardiovascular risk.
- Management strategies can target RHR to mitigate cardiovascular risk in various populations.
- Further research into RHR modulation is warranted.
Abstract:
Heart rate is a parameter that is very easy to measure and is widely used both in clinic and during daily life activities. Its value gained more relevance with the evidence, in prospective studies and meta-analysis, of association between elevated heart rate values and diseases and outcomes.The increased knowledge of physiological mechanisms of heart rate control and the pathophysiological mechanisms responsible for its dysfunction allows to identify the cut-off value of normalcy providing info for non-pharmacological and pharmacological treatments to reduce the cardiovascular risk both in general population and in pathophysiological conditions. This paper overviews the knowledges of the role of resting heart rate as predictor of cardiovascular risk.
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