Endocrine vigilance in COVID-19

Fritz-Line Velayoudom1, Piyumi Sachindra Alwis Wijewickrama2, H Ishara Ranathunga2

  • 1Department of Diabetology-Endocrinology, University Hospital of Guadeloupe , Guadeloupe.

Insights

Patients with chronic endocrine diseases should continue treatment if infected with SARS-CoV-2 (COVID-19). Hormone replacement doses may need adjustment, and monitoring is crucial for managing thyroid, adrenal, gonadal, and pituitary functions.

Area of Science:

  • Endocrinology
  • Infectious Diseases
  • Virology

Background:

  • Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes a pandemic with diverse clinical presentations.
  • The effect of SARS-CoV-2 on endocrine glands is not fully understood.
  • Previous research on related viruses suggests potential impacts on endocrine function.

Purpose of the Study:

  • To provide guidance for managing patients with chronic endocrine diseases during the SARS-CoV-2 pandemic.
  • To outline necessary adjustments in treatment and monitoring for endocrine disorders in the context of COVID-19.

Main Methods:

  • Review of existing literature on viral impacts on endocrine systems.
  • Clinical recommendations based on current understanding of SARS-CoV-2 and endocrine pathophysiology.
  • Proposal of management strategies for specific endocrine glands (thyroid, adrenals, gonads, pituitary).

Main Results:

  • Patients with chronic endocrine conditions should not discontinue their treatments when infected with SARS-CoV-2.
  • Hormone replacement therapy doses may require upward adjustments in some cases.
  • Hormonal biological monitoring is recommended in case of clinical deterioration.

Conclusions:

  • This article offers practical proposals for the management of chronic endocrine diseases (thyroid, adrenal, gonadal, pituitary) in patients affected by or exposed to SARS-CoV-2.
  • Adherence to treatment and vigilant monitoring are key to managing endocrine function during the COVID-19 pandemic.

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